摘要
目的:观察行气活血汤联合雌-孕激素序贯疗法治疗气滞血瘀型人工流产术后月经过少的临床疗效。方法:将350例气滞血瘀型人工流产术后月经过少患者按随机数字表法分为研究组和对照组各175例。对照组予雌-孕激素序贯疗法治疗,研究组予行气活血汤联合雌-孕激素序贯疗法治疗,连续治疗3个月经周期。治疗前后评定中医证候评分,记录月经量和子宫内膜厚度,检测性激素指标[卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E_(2))、催乳素(PRL)],统计治疗期间的药物不良反应发生率,比较2组的临床疗效。治疗结束后随访6个月,统计复发率。结果:治疗3个月经周期后,研究组总有效率高于对照组(P<0.05)。2组月经量、子宫内膜厚度均较治疗前增加(P<0.05);研究组月经量多于对照组,子宫内膜厚度较对照组增加,差异均有统计学意义(P<0.05)。2组血清FSH、LH、E_(2)含量均较治疗前升高,PRL含量均较治疗前下降,差异均有统计学意义(P<0.05)。研究组血清FSH、LH、E_(2)含量均高于对照组,PRL含量低于对照组,差异均有统计学意义(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。研究组复发率低于对照组(P<0.05)。结论:行气活血汤联合雌-孕激素序贯疗法可提高治疗气滞血瘀型人工流产术后月经过少的临床疗效,促进子宫内膜修复更新,调节性激素水平,改善月经失调,减少复发。
Objective:To observe the clinical effect of Xingqi Huoxue Decoction combined with estrogen and progesterone sequential therapy on scanty menstruation after induced abortion of qi stagnation and blood stasis type.Methods:A total of 350 cases of patients with scanty menstruation after induced abortion of qi stagnation and blood stasis type were divided into the study group and the control group according to the random number table method,with 175 cases in each group.The control group was treated with estrogen and progesterone sequential therapy,and the study group was treated with Xingqi Huoxue Decoction combined with estrogen and progesterone sequential therapy.Both groups were continuously treated for 3 menstrual cycles.Before and after treatment,traditional Chinese medicine syndrome scores were evaluated;menstrual volume and endometrial thickness were recorded;sexual hormone indicators [follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E_(2)),and prolactin(PRL)] were measured.The incidence of adverse drug reactions during the treatment was counted.Clinical effects were compared between the two groups.The recurrence rate during the 6-month follow-up after treatment was counted.Results:After treatment for 3 menstrual cycles,the total effective rate in the study group was higher than that in the control group(P<0.05).Menstrual volume and endometrial thickness in the two groups were increased when compared with those before treatment(P<0.05);menstrual volume and endometrial thickness in the study group were more than those in the control group,differences being significant(P<0.05).The contents of FSH,LH,and E_(2)in serum in the two groups were increased when compared with those before treatment,and PRL contents in serum were decreased,differences being significant(P<0.05).The contents of FSH,LH,and E_(2)in serum in the study group were higher than those in the control group,and PRL content in serum in the study group was lower than that in the control group,differences being significant(P<0.05).The
作者
童燕萍
李素芬
吴群
TONG Yanping;LI Sufen;WU Qun(Department of family planning,Ninghai County Maternal and Child Health Care Hospital,Ninghai Zhejiang 315600,China)
出处
《新中医》
CAS
2023年第24期46-50,共5页
New Chinese Medicine
关键词
月经过少
人工流产
气滞血瘀证
行气活血汤
性激素
月经量
子宫内膜厚度
Scanty menstruation:Induced abortion
Qi stagnation and blood stasis syndrome
Xingqi Huoxue Decoction
Sex hormones
Menstrual volume
Endometrial thickness
