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加味枸橘汤联合康复操在卵巢巧克力囊肿腹腔镜剥除术后的应用研究

Study on Application of Modified Gouju Decoction Combined with Rehabilitation Exercise in Patients After Laparoscopic Stripping of Chocolate Cyst of Ovary
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摘要 目的:观察加味枸橘汤联合康复操治疗卵巢巧克力囊肿行腹腔镜剥除术后患者的临床疗效。方法:选取卵巢巧克力囊肿行腹腔镜剥除术患者78例进行研究,按随机数字表法分为观察组与对照组各39例。2组均于术后6 h实施康复操训练,并予以促性腺激素释放激素激动剂(GnRHa)肌肉注射,观察组在对照组基础上加用加味枸橘汤治疗。治疗4周后,比较2组临床疗效、临床症状评分,治疗前后中医证候评分、血清性激素[促黄体生成素(LH)、孕酮(P)、雌二醇(E_(2))、卵泡刺激素(FSH)]及卵巢基质动脉血流动力学指标[收缩期血流峰值速度(PSV)、搏动指数(PI)、阻力指数(RI)、动脉直径(D)]水平。结果:观察组总有效率为97.44%,对照组为82.05%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组痛经、月经不调、性交痛、神疲乏力、腰膝酸软、带下量多、易怒烦躁等中医证候评分均较术前降低(P<0.05),且观察组各项评分均低于对照组(P<0.05)。治疗后,观察组盆腔疼痛、下腹部疼痛、髂窝疼痛、背部疼痛评分均低于对照组,差异有统计学意义(P<0.05)。治疗后,2组血清LH、FSH水平均较术前升高(P<0.05),P、E_(2)水平均较术前降低(P<0.05);且观察组LH、FSH水平高于对照组(P<0.05),P、E_(2)水平低于对照组(P<0.05)。治疗后,2组PSV、PI、D值均较术前升高(P<0.05),RI值较术前降低(P<0.05);且观察组PSV、PI、D值高于对照组(P<0.05),RI值低于对照组(P<0.05)。结论:卵巢巧克力囊肿患者行腹腔镜剥除术后给予加味枸橘汤联合康复操治疗,有助于改善临床症状,有效减轻术后盆腔疼痛,改善卵巢功能及血液循环。 Objective:To observe the clinical effect of Modified Gouju Decoction combined with rehabilitation exercise after laparoscopic stripping of chocolate cyst of ovary.Methods:A total of 78 cases of patients with chocolate cyst of ovary who underwent laparoscopic stripping were selected for study,and were divided into the observation group and the control group according to the random number table method,with 39 cases in each group.Both groups were given rehabilitation exercise training in 6 hours after surgery,and were given intramuscular injection with gonadotropin-releasing hormone agonist(GnRHa);the observation group was additionally treated with Modified Gouju Decoction based on the treatment of the control group.After 4 weeks of treatment,traditional Chinese medicine(TCM) syndrome scores,levels of serum sex hormones [luteinizing hormone(LH),progesterone(P),estradiol(E_(2)),follicle stimulating hormone(FSH)] and hemodynamic indexes of ovarian stromal artery [peak systolic velocity(PSV),pulsatility index(PI),resistance index(RI),and aortic diameter(D)] before and after treatment,as well as clinical effects,and clinical symptom scores were compared between the two groups.Results:The total effective rate was 97.44% in the observation group and 82.05% in the control group,the difference being significant(P<0.05).After treatment,the scores of TCM syndromes such as dysmenorrhea,irregular menstruation,algopareunia,mental fatigue and lack of strength,soreness and weakness of waist and knees,large leukorrhea amount,irascibility,and vexation and agitation in the two groups were decreased when compared with those before surgery(P<0.05),and all the above scores in the observation group were lower than those in the control group(P<0.05).After treatment,the scores of pelvic,lower abdominal pain,liac fossa pain,and back pain in the observation group were lower than those in the control group,the difference being significant(P<0.05).After treatment,the levels of LH and FSH in serum in the two groups were increased when compared
作者 陈挺雪 沈丹 阮婴丹 陈健花 CHEN Tingxue;SHEN Dan;RUAN Yingdan;CHEN Jianhua(Department of Rehabilitation,The First People's Hospital of Taizhou,Taizhou Zhejiang 318000,China;Department of Chinese Medicine,The First People's Hospital of Taizhou,Taizhou Zhejiang 318000,China)
出处 《新中医》 CAS 2023年第24期31-35,共5页 New Chinese Medicine
基金 2013年浙江省中医药科学研究基金计划(B类)(2013ZB144)。
关键词 卵巢巧克力囊肿 腹腔镜剥除术 加味枸橘汤 康复操 盆腔疼痛 Chocolate cyst of ovary Laparoscopic stripping:Modified Gouju Decoction Rehabilitation exercise Pelvic pain
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