摘要
目的回顾性分析南京鼓楼医院使用沙库巴曲缬沙坦患者住院期间用药情况,为临床合理用药提供参考。方法系统收集该院2019年7月—2021年9月使用沙库巴曲缬沙坦住院患者相关数据,对其用药合理性进行评价。结果共收集2682例次患者资料,有868例次(32.36%)患者发生918次不合理用药现象。具体不合理用药情况为:超适应证用药182次,用法用量不合理389次,药物转换不合理251次,特殊人群用药不合理96次。结论该院使用沙库巴曲缬沙坦存在不合理用药情况,临床药师应在一定程度上参与患者的用药管理,加强用药监护,提高用药合理性。
Objective To retrospective analyze the use of inpatients taking sacubitril/valsartan in Nanjing Drum Tower Hospital,and to provide references for rational clinical application.Methods The relevant data of inpatients taking sacubitril/valsartan in our hospital were systematically collected from July 2019 to September 2021,and the rationality of drug use was evaluated.Results A total of 2682 cases were collected,and 868 cases(32.36%)of them involved 918 times of irrational drug use.The specific situations of irrational drug use included off-label use(182 times),irrational usage and dosage(389 times),irrational conversation of drugs(251 times),and irrational drug use for special populations(96 times).Conclusion The use of sacubitril/valsartan exists in unreasonable situations in our hospital.Clinical pharmacists should participate in medication management to a certain extent,strengthen the pharmaceutical care of patients,and improve the rational rate of drug use.
作者
曹馨瑞
张若彬
刘紫秋
严思敏
葛卫红
CAO Xinrui;ZHANG Ruobin;LIU Ziqiu;YAN Simin;GE Weihong(Department of Pharmacy,Nanjing Drum Tower Hospital,Nanjing Drum Tower Clinical College,Nanjing University of Chinese Medicine,Nanjing 210029,China;Department of Pharmacy,Nanjing Drum Tower Hospital,School of Basic Medicine and Clinical Pharmacy,China Pharmaceutical University,Nanjing 210009,China;Department of Pharmacy,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210008,China)
出处
《医药导报》
CAS
北大核心
2024年第3期457-463,共7页
Herald of Medicine
基金
江苏省研究型医院学会精益化用药科研基金资助项目(JY202122)
江苏省药学会恒瑞医院药学基金资助项目(H202020)。
