摘要
目的探究益生菌对妊娠期糖尿病(GDM)患者血糖的影响。方法选取100例GDM患者,采用随机抽签法对其进行分组,每组50例。治疗组采用生活方式干预联合益生菌制剂干预,对照组采用生活方式干预联合安慰剂口服。对比两组患者临床效果。结果干预后,治疗组空腹血糖、餐后2h血糖、空腹胰岛素(FINS)、胰岛素抵抗指数(HOMA-IR)及胰岛素分泌指数(HOMA-β)指标改善优于对照组(P<0.05)。治疗组妊娠不良结局发生率4.00%明显低于对照组的16.00%(P<0.05)。结论益生菌可改善GDM患者的血糖水平,降低妊娠不良结局发生率,值得临床推广。
Objective To explore the effect of probiotics on blood glucose in gestational diabetes mellitus(GDM).Methods 100 patients with GDM were selected and divided into groups by random drawing method,with 50 cases in each group.The treatment group was treated with lifestyle intervention combined with probiotics,and the control group was treated with lifestyle intervention combined with oral placebo.The clinical effect of the two groups was compared.Results After intervention,fasting blood glucose,2 h postprandish blood glucose,fasting insulin(FINS),insulin resistance index(HOMA-IR)and insulin secretion index(HOMA-β)in the treatment group were better than those in the control group(P<0.05).The incidence of adverse pregnancy outcome in the treatment group(4.00%)was significantly lower than that in the control group(16.00%)(P<0.05).Conclusion Probiotics can improve the blood sugar level of GDM patients and reduce the incidence of adverse pregnancy outcomes,which is worthy of clinical promotion.
作者
麦今宝
苏艳华
徐晓
郑望德
Mai Jinbao;Su Yanhua;Xu Xiao;Zheng Wangde(Department of Obstetrics,The Eighth People's Hospital of Dongguan,Dongguan 523320,China)
出处
《实用妇科内分泌电子杂志》
2023年第31期97-101,共5页
Electronic Journal of Practical Gynecological Endocrinology
关键词
益生菌
妊娠期糖尿病
妊娠结局
Probiotics
Gestational diabetes mellitus
Pregnancy outcome
