摘要
目的:探究40岁及以下青年高血压人群臂间收缩压差异(sIAD)的影响因素。方法:选取参加2010~2020年体检的40岁及以下青年开滦职工12895例,均获取卧位同步测量四肢血压值,按照性别、年龄(±1岁)1:1匹配高血压组(n=3584)和非高血压组(n=3584),每组再进一步根据sIAD分为sIAD<10 mmHg(1 mmHg=0.133 kPa)者和sIAD≥10 mmHg者。采用逐步多因素Logistic回归模型分析两组sIAD≥10 mmHg的影响因素。结果:高血压组的sIAD≥10 mmHg检出率高于非高血压组(31.72%vs.27.76%,P<0.001)。逐步多因素Logistic回归结果显示,高血压人群中,踝臂指数(ABI)<0.9、男性、肥胖、超重、低密度脂蛋白胆固醇(LDL-C)水平升高、收缩压升高均与sIAD≥10 mmHg呈正相关(P均<0.05);大学及以上学历、体育锻炼均与sIAD≥10 mmHg呈负相关(P均<0.05)。非高血压人群中,ABI<0.9、收缩压升高均与sIAD≥10 mmHg呈正相关(P均<0.05);年龄增长与sIAD≥10 mmHg呈负相关(P均<0.05)。结论:青年高血压人群sIAD≥10 mmHg检出率高于青年非高血压人群。ABI降低、男性、肥胖、超重、LDL-C水平升高、收缩压升高、大学及以上学历和体育锻炼是青年高血压人群sIAD≥10 mmHg的影响因素。
Objectives:To explore the influencing factors of inter-arm systolic blood pressure difference(sIAD)in young hypertensive population.Methods:A total of 12895 young Kailuan employees aged≤40 years,who participated in the physical examination from 2010 to 2020,were enrolled in this study.All of them underwent blood pressure measurements of four limbs in supine position.Young hypertensive group(n=3584)and young non-hypertensive group(n=3584)were 1:1 matched by sex and age(±1 year),and participants were further divided into sIAD<10 mmHg(1 mmHg=0.133 kPa)and sIAD≥10 mmHg subgroups.A stepwise multivariate logistic regression model was established to analyze the determinants of sIAD≥10 mmHg.Results:The detection rate of sIAD≥10 mmHg was significantly higher in the young hypertensive group than in the young non-hypertensive group(31.72%vs.27.76%,P<0.001).Stepwise multivariate logistic regression analysis showed that in young hypertensive population,ankle-brachial index(ABI)<0.9,male,obesity,overweight,elevated low density lipoprotein cholesterol(LDL-C)level,and systolic blood pressure were positively associated with sIAD≥10 mmHg,while college education or above,physical exercise were negatively correlated with sIAD≥10 mmHg(all P<0.05).In the young nonhypertensive population,ABI<0.9,systolic blood pressure were positively correlated with sIAD≥10 mmHg,while age was negatively associated with sIAD≥10 mmHg(all P<0.05).Conclusions:The detection rate of sIAD≥10 mmHg is higher in young hypertensive population than in young nonhypertensive population.Decreased ABI,male sex,obesity,overweight,increased LDL-C level,systolic blood pressure,college education and above,and physical exercise are the influencing factors of sIAD≥10 mmHg in young hypertensive population.
作者
曹启环
苏亦男
朱颖
董文丽
王羽茜
葛静
吴寿岭
CAO Qihuan;SU Yinan;ZHU Ying;DONG Wenli;WANG Yuxi;GE Jing;WU Shouling(College of Nursing and Rehabilitation,North China University of Science and Technology,Tangshan 063000,China;Chronic Disease Management Department,The First Affiliated Hospital of Hebei North University,Zhangjiakou 075000,China;Department of Cardiology,Kailuan General Hospital,Tangshan 063000,China)
出处
《中国循环杂志》
CSCD
北大核心
2024年第2期164-170,共7页
Chinese Circulation Journal
基金
河北省2021年度医学科学研究课题计划项目(20211802)。
关键词
青年
高血压
臂间收缩压差异
检出率
影响因素
youth
hypertension
inter-arm systolic blood pressure difference
detection rate
influencing factors
