摘要
目的对氨基葡萄糖进行药品临床快速综合评价,为医疗机构遴选氨基葡萄糖提供依据。方法结合上海中医药大学附属市中医医院与上海市的实际情况,参照《中国医疗机构药品评价与遴选快速指南(第二版)》,从药学特性、有效性、安全性、经济性及其他属性评价盐酸氨基葡萄糖胶囊(商品名三康,0.75 g×30粒/瓶、0.75 g×60粒/瓶)和硫酸氨基葡萄糖胶囊(商品名伊索佳,0.314 g×12粒×2板/盒)。结果盐酸氨基葡萄糖胶囊30粒/瓶的评分为71.74分,60粒/瓶的评分为71.5分,硫酸氨基葡萄糖胶囊的评分为71.5分。结论三款氨基葡萄糖药品的药学特性、安全性及其他属性较一致,盐酸氨基葡萄糖胶囊的经济性较好,硫酸氨基葡萄糖胶囊的有效性证据更充分。
Objective To rapidly and comprehensively evaluate clinical use of glucosamine as a basis for medical institutions to select glucosamine.Methods Based on the reality of Shanghai Municipal Hospital of Traditional Chinese Medicine and Shanghai,the pharmacological properties,effectiveness,safety,economy and other indicators of Glucosamine hydrochloride capsules(SANKANG,0.75 g×30 capsules/bottle and 0.75 g×60 capsules/bottle)and Glucosamine sulfate capsules(YISUOJIA,0.314 g×12 capsules×2 plates/kit)were evaluated by referring to A Rapid Guideline for Drug Evaluation and Selection in Chinese Medical Institutions(the 2nd Edition).Results Glucosamine hydrochloride capsules 30 capsules/bottle scored 71.74,while 60 capsules/bottle scored 71.5.Glucosamine sulfate capsules scored 71.5.Conclusion The pharmaceutical properties,safety,and other indicators are consistent for all three glucosamines.Glucosamine hydrochloride capsules displays economic advantage.The evidence for the effectiveness of Glucosamine sulfate capsule is more sufficient than that of Glucosamine hydrochloride capsule.
作者
孔维崧
贾婷婷
张立超
KONG Wei-song;JIA Ting-ting;ZHANG Li-chao(Department of Pharmacy,Shanghai Municipal Hospital of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200071)
出处
《中南药学》
CAS
2024年第2期519-525,共7页
Central South Pharmacy
基金
上海市中医药三年行动计划项目[No.ZY(2021-2023)-0203-04]。
关键词
氨基葡萄糖
药品评价
药品遴选
合理用药
glucosamine
drug evaluation
drug selection
rational administration
