摘要
草乌所含的特征性成分二萜类生物碱是其主要毒性成分也是有效成分,具有抗炎、镇痛、抑菌、抗病毒、强心、抗肿瘤、局部麻醉等药理活性的同时也存在各种毒性作用。故传统医药通常通过炮制或配伍,降低其毒性,保障临床用药安全。作为中医药的重要组成部分蒙医药在这方面优势更为突出。
The characteristic ingredient diterpenoid alkaloids contained in Caowu(Aconitum Kusnezoffii Reichb)is its main toxic component and active ingredient,which has pharmacological activities such as anti-inflammatory,analgesic,bacteriostatic and antiviral,cardiotonic,antitumor,local anesthesia,etc.and also has various abnormal multi-system toxic effects.Therefore,traditional medicine is usually prepared or compounded to reduce its toxicity and ensure its safe clinical use.As an important part of traditional Chinese medicine,Mongolian medicine has more prominent advantages in this regard.
作者
乌尼日
包勒朝鲁
Wuniri;Baole Chaolu(Inner Mongolia Medical University,Hohhhot Inner Mogolia 010110,China)
出处
《中医药导报》
2024年第1期93-99,共7页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(82160790)
内蒙古医科大学蒙药学“一流学科”研究生科研能力提升计划项目(MYX2022-R13)。
关键词
草乌
化学成分
药理作用
毒性
蒙医学毒性控制
Caowu(Aconitum Kusnezoffii Reichb)
chemical composition
pharmacological action
toxicity
Mongolian medical toxicity control