摘要
目的观察新加宁心通痹汤治疗老年冠心病稳定型心绞痛(气虚血瘀兼气滞证)的临床疗效。方法将60例入组患者随机分为观察组与对照组各30例,两组均予以西医冠心病二级预防用药,观察组加予新加宁心通痹汤口服,疗程均为4周,观察两组治疗前后中医证候疗效、心绞痛改善情况、主要症状评分、西雅图心绞痛量表(SAQ)评分及心电图疗效。结果观察组总有效率为86.21%,高于对照组的71.43%(P<0.05);观察组心绞痛改善总有效率优于对照组(P<0.05);观察组治疗后胸闷、胸痛、气短、心悸症状评分明显低于对照组(P<0.05);两组患者西雅图心绞痛量表(SAQ)评分均较治疗前升高(P<0.05),观察组升高更显著(P<0.05);治疗后观察组的心电图改善优于对照组(P<0.05)。两组治疗前后血尿便三大常规、肝肾功能均未出现异常。结论新加宁心通痹汤治疗气虚血瘀兼气滞证之老年冠心病稳定型心绞痛可有效改善患者症状,提高患者生活质量。
Objective:To observe the clinical effect of Xinjia Ningxin Tongbi Decoction in the treatment of senile stable angina pectoris of coronary heart disease(syndrome of blood stasis due to qi deficiency with qi stagnation).Methods:A total of 60 patients were randomly assigned to either an observation group or a control group,and both groups were given western medicine for secondary prevention of coronary heart disease.The observation group also orlly received Xinjia Ningxin Tongbi Decoction for 4 weeks,and the efficacy of traditional Chinese medicine symptoms,improvement of angina pectoris,main symptom scores,Seattle Angina Quotient(SAQ)scores,and electrocardiogram in both groups before and after treatment were observed.Results:The total effective rate of the observation group was 86.21%,which was higher than 71.43%of the control group(P<0.05);the total effective rate of improvement of angina pectoris in the observation group was better than that in the control group(P<0.05);the scores of chest tightness,chest pain,shortness of breath and palpitation in the observation group after the treatment were significantly lower than that in the control group(P<0.05);the scores of SAQ in both groups were higher than those before the treatment(P<0.05),and the increase was more significant in the observation group(P<0.05);the improvement of electrocardiogram in the observation group was better than that in the control group after treatment(P<0.05).There were no abnormalities in the blood,urine and stool routine examinations and liver and kidney functions before and after treatment in both groups.Conclusion:Xinjia Ningxin Tongbi Decoction can effectively improve patients'symptoms and quality of life by treating senile stable angina pectoris of coronary heart disease(syndrome of blood stasis due to qi deficiency with qi stagnation).
作者
冯丹
何德英
赵磊
邹演梅
孙文
邓春香
Feng Dan;He Deying;Zhao Lei;Zou Yanmei;Sun Wen(Deng Chunxiang.Guizhou University of Traditional Chinese Medicine,Guizhou,Guiyang 550002,China)
出处
《中国中医急症》
2024年第2期287-291,共5页
Journal of Emergency in Traditional Chinese Medicine
基金
重庆市科技局重庆英才计划项目(cstc2022ycjh-bgzxm0074)。
关键词
老年冠心病
稳定型心绞痛
新加宁心通痹汤
气虚血瘀兼气滞证
Senile coronary heart disease
Stable angina pectoris
Xinjia Ningxin Tongbi Decoction
Blood stasis due to qi deficiency with qi stagnation