摘要
目的分析许昌市2019—2020年手足口病的病原体型别及分布,为手足口病的防治提供参考依据。方法采用Real-Time RT-PCR法,检测2019年1月1日-2020年12月31日间许昌市临床诊断手足口病例粪便、肛拭子、咽拭子、疱疹液标本的病毒核酸,并对监测数据进行分析。结果两年共检测标本540份,阳性409份,总阳性率75.74%,其中CA16阳性81份(占19.80%),EV71阳性11份(占2.69%),其他肠道病毒阳性280份(占68.46%),轻、重症病例肠道病毒阳性率差异无统计学意义(χ^(2)=0.37,P>0.05),不同年龄组构成比差异无统计学意义(χ^(2)=1.42,P>0.05)。结论许昌市2019—2020年手足口病的主要发病人群是3岁以下年龄组幼儿,优势毒株是其他肠道病毒,EV71型肠道病毒的阳性占比明显降低。
Objective To analysis the etiological types and distribution features of hand-foot-mouth disease in Xuchang between 2019 and 2020.Methods The specimens of stool,anus swabs,herpes fluid,throat swab of the part local clinically diagnosed cases with HFMD were collected between 2011 and 2013 in Xuchang,and the monitoring datas were analyzed.Results A total of 540 samples were tested in the past two years with 409 positive,and the total positive rate was 75.74%.Among them,81 were positive for CA16(19.80%),11 were positive for EV71(2.69%),and 280 were positive for other enterovirus(68.46%).There was no significant difference in the positive rate of enterovirus between mild and severe cases(χ^(2)=0.37,P>0.05),and no significant difference in the composition ratio among different age groups(χ^(2)=1.42,P>0.05).Conclusion The main incidence group of hand-footmouth disease in Xuchang City from 2019 to 2020 was children under 3 years old.The dominant strain was other enterovirus,and the positive proportion of EV71 enterovirus was significantly reduced.
作者
毛斐
刘克克
贾桂华
张尧
Mao Fei;Liu Keke;Jia Guihua;Zhang Yao(Xuchan Center for Disease Control and Prevention,Xuchang Henan 461000,China;Tianjin International Travel Health Tianjin Customs Port Outpatient Department,Tianjin 300450,China)
出处
《口岸卫生控制》
2024年第1期36-39,共4页
Port Health Control
关键词
手足口
病原
肠道病毒
分布
Hand-foot-mouth disease
Pathogen
Enterovirus
Distribution
