摘要
目的探究大肠癌筛查高危因素量化问卷在大肠癌伺机性筛查中的应用价值及危险因素。方法随机选取2020年1月—2023年1月上海市长宁区天山中医医院收治的健康体检和普通就诊大肠疾病风险人群3000例为研究对象,对所有受试者进行大肠癌筛查高危因素量化问卷调查及粪隐血试验,根据检测结果决定是否进行直肠指检及肠镜检查。分析筛查结果及结直肠癌的相关危险因素。结果伺机性筛查初筛中有高危患者1021例,其中男性初筛阳性高危检出率55.04%高于女性的44.96%。高危受检者中肛指检查阳性29例(2.84%),结肠镜检查异常202例19.78%,结肠镜检查异常者包括结肠炎7.25%,腺瘤性息肉1.08%,结直肠癌1.47%,管状腺瘤9.99%;不同患者性别、年龄、饮食习惯、大肠息肉既往史及消化道肿瘤家族史差异有统计学意义(P<0.05),而腹型肥胖、行为习惯、排便习惯差异无统计学意义(P>0.05);logistic回归性分析结果表明饮食习惯、大肠息肉既往史以及消化道肿瘤家族史与患结直肠癌呈正相关(P<0.05),而年龄与患结直肠癌无相关性(P>0.05)。结论大肠癌筛查高危因素量化问卷在大肠癌伺机性筛查中具有良好的应用价值,有利于根据相关危险因素筛查出结直肠癌患者。
Objective To explore application value and risk factors of quantitative questionnaire of high-risk factors in opportunistic screening of colorectal cancer.Methods The paper chose 3000 common individuals with colorectal disease risks admitted to Shanghai Changning District Tianshan Traditional Chinese Medicine Hospital from January 2020 to January 2023 as study subjects,treated with quantitative questionnaire survey on high-risk factors for colorectal cancer screening and fecal occult blood test.Based on the test results,rectal digital examination and colonoscopy was determined.Screening results and related risk factors for colorectal cancer were analyzed.Results There were 1021 high-risk patients during initial screening of opportunistic screening,with a positive high-risk detection rate of 55.04% for males,higher than 44.96% for females.Among high-risk subjects,29 cases(2.84%)showed positive by anal finger test,202 cases(19.78%)showed abnormal by colonoscopy,including 7.25% of colonitis,1.08% of adenomatous polyps,1.47% of colorectal cancer,and 9.99% of tubular adenomas.There was statistically significant difference in gender,age,dietary habits,past history of colorectal polyps,and family history of gastrointestinal tumors(P<0.05),there was no statistically significant difference in abdominal obesity,behavioral habits,and bowel habits(P>0.05).Logistic regression analysis showed dietary habits,past history of colorectal polyps,and family history of gastrointestinal tumors were positively correlated with colorectal cancer(P<0.05),while age was not correlated with colorectal cancer(P>0.05).Conclusion Quantitative questionnaire of high-risk factors in colorectal cancer screening has good application value in opportunistic screening of colorectal cancer,which is beneficial for screening colorectal cancer patients based on related risk factors.
作者
周健
丁海君
唐学典
郭建娣
田君
ZHOU Jian;DING Haijun;TANG Xuedian;GUO Jiandi;TIAN Jun(General Surgery Department,Changning District Tianshan Traditional Chinese Medicine Hospital,Shanghai 200051;Endoscopy Center,Changning District Tianshan Traditional Chinese Medicine Hospital,Shanghai 200051;Department of Internal Medicine,Changning District Tianshan Traditional Chinese Medicine Hospital,Shanghai 200051)
出处
《智慧健康》
2023年第27期40-44,共5页
Smart Healthcare
基金
2018年度长宁区天山中医医院科研项目《大肠癌伺机性筛查模式的临床研究》(项目编号:2018TSKY05)。
关键词
大肠癌筛查
高危因素量化问卷
大肠癌伺机性筛查
应用价值
危险因素
Colorectal cancer screening
High risk factor quantification questionnaire
Opportunistic screening for colorectal cancer
Application value
Risk factors
