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微创与开颅手术在脑出血治疗中的疗效及安全性比较分析

Comparative Analysis of Effect and Safety of Minimally Invasive and Craniotomy Surgery in Treatment of Cerebral Hemorrhage
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摘要 目的探讨微创与开颅手术在脑出血治疗中的疗效及安全性比较分析。方法选取2019年1月—2021年12月脑出血患者中挑选100例为研究对象,并随机分为对照组(50例)、研究组(50例)。对照组接受开颅手术方式,研究组运用微创治疗方式。比较两组治疗效果、手术指标、炎症反应、术后并发症。结果研究组治疗总有效率高于对照组(P<0.05);研究组切口长度、骨窗面积及手术时间缩短于对照组,术中出血量少于对照组,血肿清除率高于对照组(P<0.05);研究组的治疗后血清TNF-a(肿瘤坏死因子-a)、血清hs-CRP(超敏C反应蛋白)、血清IL-6(白细胞介素-6)指标低于对照组(P<0.05);研究组的术后并发症率低于对照组(P<0.05)。结论在脑出血治疗中应用微创治疗方式较传统开颅手术更具优势,能够更改善手术指标,改善炎症反应,提高疗效效果,且安全性更高,其临床应用效果更值得。 Objective To compare and analyze effect and safety of minimally invasive and craniotomy surgery for cerebral hemorrhage.Methods The paper chose 100 patients with cerebral hemorrhage from January 2019 to December 2021 as study subjects,and divided them into control group(50 cases)and study group(50 cases)randomly.Control group was treated with craniotomy,while study group with minimally invasive treatment.Treatment effect,surgical indicators,inflammatory reactions,and postoperative complications was compared between two groups.Results Total effective rate of study group was higher than control group(P<0.05).Incision length,bone window area,and surgical time in study group was shorter than control group,with less intraoperative bleeding and higher hematoMA clearance rate(P<0.05).After treatment,serum TNF-a(tumor necrosis factor-a),hs-CRP(hypersensitive C-reactive protein),and IL-6(interleukin-6)indicators in study group were lower than control group(P<0.05).Postoperative complication incidence in study group was lower than control group(P<0.05).Conclusion Minimally invasive treatment can achieve more advantages than traditional craniotomy cerebral hemorrhage,can change surgical indicators,improve inflammatory reactions,and curative effect,with higher safety and more worthwhile clinical application effect.
作者 张朔 ZHANG Shuo(Neurosurgery Department,Zibo City Zichuan District Hospital,Zibo,Shandong,255100)
出处 《智慧健康》 2023年第25期155-158,162,共5页 Smart Healthcare
关键词 开颅手术 脑出血 微创手术 疗效 炎症反应 安全性 术后并发症 Craniotomy surgery Cerebral hemorrhage Minimally invasive surgery Effect Inflammatory response Safety Postoperative complications
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