摘要
目的比较shii评分、 肌少症筛查5项评分量表(Strength, Assistance with Walking, Rise from aChair, Climb Stairs and Falls , SARC-F).肌少症筛查5项评分联合小腿围量表(SARC-F and Calf Circumferen-ce, SARC-CalF)及迷你肌少症风险评估-7条目问卷(Mini Sarcopenia Risk Assessment-7 ,MSRA-7)筛查慢性肝病患者肌少症的相对准确性。方法该前瞻性研究纳人366例慢性肝病患者。应用Ishii评分.SARC-F、SARC-CalF和MSRA-7对患者进行筛查。肌少症由临床医生根据亚洲肌少症工作组(AsiaWorkingGroupforSarco-penia,AWGS)2019标准进行诊断,以此为金标准对4种筛查工具的性能进行比较。结果基于AWGS2019标准,本组慢性肝病患者的肌少症患病率为17.5%。Ishii评分、SARC-F .SARC-CalF和MSRA-7的受试者工作特征(receiver operating characteristic, ROC)曲线下面积(敏感度,特异度)分别为0.820(8594% ,78.15%)、0.528(6.25% , 99.34%) 0.642(45.31% , 83.1 1%).0.552(87.50% ,22.85%)。根据ROC曲线下面积、决策曲线以及校准曲线分析结果,Ishi评分筛查馒性肝病患者肌少症的性能优于其他3个工具(P<0.0001)。结论Ishii评分比SARC-F.SARC-CalF和MSRA-7更适合用于筛查馒性肝病患者的肌少症。护士在临床工作中可应用Ishii评分对慢性肝病患者进行肌少症筛查,早期发现肌少症风险,为进一步诊断肌少症提供依据。
Objectives:Early identification of sarcopenia in patients with chronic liver disease is crucial for patient management and prevention of severe complications.We aimed to assess the effectiveness of Ishii score,Strength,Assistance with Walking,Rise from a Chair,Climb Stairs and Falls(SARC-F),SARC-F and Calf Circumference(SARC-CalF),and Mini Sarcopenia Risk Assessment-7(MSRA-7)to screen sarcopenia in patients with chronic liver disease.Methods:This prospective study included patients with chronic liver disease in the infectious department of a tertiary hospital in Sichuan,China.Ishii score,SARC-F,SARC-CalF,and MSRA-7 were used to screen for sarcopenia risk.Sarcopenia was diagnosed according to the Asian Myometriosis Working Group(AWGS)2019,which was used as the gold standard to compare the performance of the four screening tools.We completed clinical registration on the Chinese Clinical Trial Registration website(ChiCTR2100043910).Results:A total of 366 patients with chronic liver disease(22.4%women,mean age 48.96±11.88 years)were evaluated.Based on the AWGS 2019 standard,the prevalence of sarcopenia in patients with chronic liver disease was 17.5%.Among all participants,receiver operating characteristic(ROC)produced an area under the curve(AUC)of 0.82 for Ishii score(sensitivity 85.94%,specificity 78.15%),0.53 for SARC-F(sensitivity 6.25%,specificity 99.34%),0.64 for SARC-CalF(sensitivity 45.31%,specificity 83.11%),and 0.55 for MSRA-7(sensitivity 87.50%,specificity 22.85%).Based on AUC,decision curve analysis,and calibration curves,we concluded that Ishii score was the most accurate screening tool and was superior to the other tools.Conclusions:Ishii score is more suitable for screening sarcopenia in patients with chronic liver disease than the SARC-F,SARC-CalF,and MSRA-7,based on the AWGS 2019 criteria.Nursing professionals can use Ishii score as a clinical tool to screen for sarcopenia in patients with chronic liver disease,providing an indication cue for the final diagnosis of sarcopenia,improving diagnostic e
作者
喻婷
刘珊珊
赵静
蒋艳
邓蓉
Ting Yu;Shanshan Liu;Jing Zhao;Yan Jiang;Rong Deng(Department of Evidence-based Nursing Center,West China Hospital,Sichuan University/West China School of Nursing,Sichuan University,Chengdu,China;Department of Nursing,West China Hospital,Sichuan University/West China School of Nursing,Sichuan University,Chengdu,China;Center of Infectious Diseases,West China Hospital,Sichuan University/West China School of Nursing,Sichuan University,Chengdu,China)
