摘要
提出一种应用于光学相干层析成像(OCT)的色散补偿方法,目的是抑制点扩散函数的轴向展宽并提高系统的信噪比。基于信号空域脉冲随色散的退化性质,构建出信号空域脉宽平方对二阶色散平方的线性方程组,然后将色散增量引入原始信号得到新的信号,并代入方程组即可求解出原始信号的二阶色散,进一步构建补偿相位对原始信号进行色散校正。将该方法应用在点扩散函数修正和生物组织图像的色散补偿中,实验结果表明:点扩散函数的峰值信噪比提高5.11 dB,在效果相近的情况下,所提方法比迭代法快5倍,比分数阶傅里叶变换(FrFT)法快50倍。校正后图像的轴向分辨能力和对比度得到提高,生物样品的结构特征更加清晰。
Objective Optical coherence tomography(OCT)is a pivotal biomedical imaging technique based on the low coherence interference principle.It facilitates the production of tomographic scans of biological tissues,extensively applied to medical fields such as ophthalmology and dermatology.However,the pursuit of heightened axial resolution compels OCT systems to harness broadband light sources,and it is an approach that inadvertently introduces dispersion effects and gives rise to imaging artifacts,blurring,and consequently diminished image quality.Therefore,it is necessary to conduct dispersion compensation in OCT systems.While hardware-based compensation techniques are plagued by increased costs and complexity,their efficacy remains limited,which spurs the exploration and application of more flexible dispersion compensation algorithms.However,commonly employed algorithms based on search strategies suffer from suboptimal adaptability and concealed computational intricacies.Thus,we introduce an innovative dispersion compensation algorithm established based on the concept of spatial pulse degradation resulting from dispersion.The algorithm integrated into frequency domain OCT system experiments eliminates the requirements for manual dispersion range adjustments.Meanwhile,it features notable computational efficiency to offset the shortcomings of conventional search strategies in adaptability and computational efficacy.The proposed method is proven to be instrumental in enhancing the engineering practicality of OCT systems and improving the quality of tomographic images.Methods We propose an efficient dispersion compensation algorithm grounded in spatial pulse degradation due to dispersion and apply it to frequency domain OCT system experiments.The algorithm consists of two parts including dispersion extraction and compensation.By adopting the principle that dispersion causes widening spatial pulse,the algorithm estimates the dispersion of the signal to be corrected and subsequently applies compensation.A linear equation e
作者
徐玉帅
蔡怀宇
王露桐
汪毅
陈晓冬
Xu Yushuai;Cai Huaiyu;Wang Lutong;Wang Yi;Chen Xiaodong(Key Laboratory of Opto-Electronics Information Technology of Ministry of Education,School of Precision Instrument and Opto-Electronics Engineering,Tianjin University,Tianjin 300072,China)
出处
《光学学报》
EI
CAS
CSCD
北大核心
2023年第23期99-106,共8页
Acta Optica Sinica
关键词
光学相干层析成像
色散补偿
二阶色散
空域脉冲宽度
optical coherence tomograph
dispersion compensation
second-order dispersion
spatial pulse width
