摘要
目的:采用Meta分析方法评估我国慢性阻塞性肺疾病(COPD)病人认知障碍的患病率。方法:从中国知网数据库、万方数据库、维普数据库、PubMed、Web of Science数据库中检索相关文章,根据纳入排除标准筛选文章,由2名研究者进行严格的文献质量评价,应用Stata 16.0软件进行Meta分析,并根据不同的年龄、性别、文化程度、吸烟史进行亚组分析。结果:共纳入15篇文献,包括2805例COPD病人,其中1415例病人合并认知障碍。Meta分析结果显示:中国COPD病人认知障碍的总患病率为53.0%[95%CI(43.05%,64.0%)]。亚组分析结果:60岁以下COPD病人认知障碍的患病率为40.0%[95%CI(21.0%,58.0%)],60岁及以上COPD病人认知障碍的患病率为59.0%[95%CI(42.0%,76.0%)];男性COPD病人认知障碍的患病率为52.0%[95%CI(38.0%,66.0%)],女性COPD病人认知障碍的患病率为55.0%[95%CI(37.0%,74.0%)];小学及以下学历的COPD病人认知障碍的患病率为66.0%[95%CI(43.0%,88.0%)],初中学历的COPD病人认知障碍的患病率为76.0%[95%CI(64.0%,89.0%)],高中/中专学历的COPD病人认知障碍的患病率为54.0%[95%CI(30.0%,77.0%)],本科/专科学历的COPD病人认知障碍的患病率为35.0%[95%CI(20.0%,50.0%)];无吸烟史的COPD病人认知障碍的患病率为37.0%[95%CI(18.0%,57.0%)],已戒烟的COPD病人认知障碍的患病率为56.0%[95%CI(33.0%,80.0%)],仍未戒烟的COPD病人认知障碍的患病率为64.0%[95%CI(40.0%,87.0%)]。结论:我国COPD病人认知障碍的患病率较高,应早期识别危险因素,积极预防及干预。
Objective:To assess the prevalence of cognitive impairment in patients with chronic obstructive pulmonary disease(COPD)in China by using Meta-analysis.Methods:Relevant articles were retrieved from China National Knowledge Infrastructure(CNKI),Wanfang database,Vip database,Pubmed,and Web of Science database.Articles were screened according to the inclusion and exclusion criteria.Two researchers conducted strict literature quality evaluation and performed meta-analysis using Stata16.0 software.Subgroup analysis was performed according to different ages,genders,education levels,and smoking history.Results:A total of 15 articles were included,involving 2805 patients with COPD,of which 1415 patients with cognitive impairment.Meta-analysis results showed that the total prevalence of cognitive impairment in Chinese patients with COPD was 53.0%[95%CI(43.0%,64.0%)].Subgroup analysis results showed that the prevalence of cognitive impairment in patients with COPD under 60 years old was 40.0%[95%CI(21.0%,58.0%)]and who over 60 years old was 59.0%[95%CI(42.0%,76.0%)];52.0%[95%CI(38.0%,66.0%)]for male patients and 55.0%[95%CI(37.0%,74.0%)]for female patients;66.0%[95%CI(43.0%,88.0%)]for patients with primary school education and below,76.0%[95%CI(64.0%,89.0%)]for patients with junior high school education,54.0%[95%CI(30.0%,77.0%)]for patients with senior high school/technical secondary school education,and 35.0%[95%CI(20.0%,50.0%)]for patients with college/junior college education;37.0%[95%CI(18.0%,57.0%)]for patients without smoking history,56.0%[95%CI(33.0%,80.0%)]for those who have quit smoking,and 64.0%[95%CI(40.0%,87.0%)]for those who have not quit smoking.Conclusions:The prevalence of cognitive impairment in COPD patients in China is high,so we should identify risk factors early and actively prevent and intervene.
作者
陈云晓
唐文婷
戴冬梅
CHEN Yunxiao;TANG Wenting;DAI Dongmei(School of Nursing,Shandong First Medical University,Shandong Academy of Medical Sciences,Shandong 271016 China)
出处
《全科护理》
2024年第3期406-410,共5页
Chinese General Practice Nursing
关键词
慢性阻塞性肺疾病
认知障碍
患病率
META分析
chronic obstructive pulmonary disease,COPD
cognitive impairment
prevalence
Meta-analysis
