摘要
目的探讨辽宁省金秋医院使用达格列净药物的患者年龄、性别分布情况,以及该药与其他降糖药物联用情况,为一线临床人员选用该药物提供临床参考。方法从辽宁省金秋医院中联医院信息(HIS)系统中抽取辽宁省金秋医院2021年4月至2022年7月应用达格列净药物的门诊处方为研究对象进行整理分析。应用Excel进行统计分析患者的年龄、性别,口服达格列净以及达格列净与其他降糖药物联用情况。结果辽宁省金秋医院使用达格列净药物治疗2型糖尿病患者的处方中,男性患者处方714张(71.4%),女性患者处方286张(28.6%),男性患者多于女性患者。该药物在60~74岁年龄组使用比例最高,门诊处方478张(47.8%)。在达格列净与其他口服降糖药物联用的600张处方中,以单用达格列净最多,处方数272张(45.33%),其次是与其他一种口服降糖药联用,处方数238(39.67%),其中与双胍类联用最多,处方数98张(41.18%),与其他两种或者更多种口服降糖药联用较少。在达格列净与胰岛素联用的400张处方中,与中、长效胰岛素联用最多,处方一共352张(88%),与预混胰岛素联用以及与中效和超短效联用的处方数相同,52张处方(13%)。结论辽宁省金秋医院使用达格列净与其它降糖药物联用治疗2型糖尿病患者的用药特点是:达格列净联合中、长效胰岛素控制血糖最多,其次是单用达格列净,如需与其他口服降糖药物联用,多与一种口服降糖药联用,其中与二甲双胍联用最多。
Objective To investigate the age and gender distribution of patients using Dapagliflozin in Liaoning Jinqiu Hospital,as well as the combined use of the drug with other hypoglycemic drugs,so as to provide clinical reference for front-line clinical personnel in selecting the drug.Methods The outpatient prescriptions of Dapagliflozin used in Liaoning Jinqiu Hospital from April 2021 to July 2022 were selected from the Zhonglian Hospital information system(HIS)of Liaoning Jinqiu Hospital and analyzed.Excel was used for statistical analysis of patients'age,gender,oral Dapagliflozin and Dapagliflozin combined with other hypoglycemic drugs.Results Among the prescriptions of Dapagliflozin for type 2 diabetes patients in Jinqiu Hospital of Liaoning Province,714 prescriptions(71.4%)were for male patients and 286 prescriptions(28.6%)were for female patients.Male patients were more than female patients.The drug has the highest usage rate in the age group of 60-74,with 478 outpatient prescriptions(47.8%).Among the 600 prescriptions of Dapagliflozin in combination with other oral hypoglycemic drugs,Dapagliflozin alone accounted for 272 prescriptions(45.33%),followed by 238 prescriptions(39.67%)in combination with other oral hypoglycemic drugs,of which 98 prescriptions(41.18%)were in combination with Biguanide,and fewer were in combination with other two or more oral hypoglycemic drugs.Among the 400 prescriptions of Dapagliflozin in combination with insulin,352 prescriptions(88%)were used in combination with medium and long-acting insulin,52 prescriptions(13%)were used in combination with premixed insulin and medium and ultra short acting insulin.Conclusion In Jinqiu Hospital of Liaoning Province,the use of Dapagliflozin in combination with other hypoglycemic drugs in the treatment of patients with type 2 diabetes is characterized by the following:Dapagliflozin in combination with medium and long-acting insulin controls blood sugar most,followed by Dapagliflozin alone.If it needs to be used in combination with other oral hypogly
作者
梁秋艳
LIANG Qiuyan(Department of Pharmacy,Liaoning Jinqiu Hospital,Liaoning Province,Shenyang110016,China)
出处
《中国当代医药》
CAS
2024年第2期129-132,共4页
China Modern Medicine
关键词
达格列净
口服降糖药物
2型糖尿病
药物联用
胰岛素
Dapagliflozin
Oral hypoglycemic drugs
Type 2 diabetes
Drug combination therapy
Insulin