摘要
目的总结对照息肉样脉络膜血管病变患者光学相干断层扫描血管成像(OCTA)与吲哚菁绿血管造影(ICGA)的图像特征。方法通过便利抽样法,选取2021年4月至2022年4月在南昌大学附属眼科医院接受治疗的50例息肉样脉络膜血管病变患者作为研究对象。所有患者在治疗前均接受OCTA与ICGA检查,以ICGA检查结果作为金标准,对OCTA与ICGA检查结果进行对照分析。结果50例患者中,ICGA检查可见特征性息肉样病灶17例,异常分支血管网21例,异常分支血管网合并特征性息肉样病灶10例,因出血遮挡无异常表现2例,检出率为96.00%(48/50)。OCTA检查可见特征性息肉样病灶16例,异常分支血管网19例,异常分支血管网合并特征性息肉样病灶11例,无异常表现4例,检出率为92.00%(46/50);两种检查方式检出率比较,差异无统计学意义(χ^(2)=0.709,P=0.400)。Kappa一致性检验分析结果显示,ICGA与OCTA诊断息肉样脉络膜血管病变具有较高一致性(Kappa=0.816,P<0.001)。以ICGA检查结果作为金标准,OCTA诊断息肉样脉络膜血管病变的敏感度、特异度、准确度分别为97.83%(45/46)、75.00%(3/4)和92.00%(46/50)。结论ICGA与OCTA诊断息肉样脉络膜血管病变的病变一致性较高,ICGA检查表现为异常分支血管网者,OCTA检查可见相似表现;ICGA检查表现为特征性息肉样病灶者,OCTA检查可见明显强信号亮点;ICGA与OCTA检查显示病灶形态及位置具有一定相似性。
Objective To summarize the image characteristics of optical coherence tomography angiography(OCTA)and indocyanine green angiography(ICGA)in patients with polypoid choroidal angiopathy.Methods By convenient sampling method,50 patients with polypoid choroidal angiopathy who were treated in the Affiliated Eye Hospital of Nanchang University from April 2021 to April 2022 were selected as the research objects.All patients underwent OCTA and ICGA examinations before treatment.The results of ICGA were used as the gold standard,and the results of OCTA and ICGA were compared and analyzed.Results Among the 50 patients,ICGA showed characteristic polypoid lesions in 17 cases,abnormal branch vascular network in 21 cases,abnormal branch vascular network with characteristic polypoid lesions in 10 cases,and no abnormal manifestations due to bleeding occlusion in 2 cases,with a detection rate of 96.00%(48/50).OCTA showed characteristic polypoid lesions in 16 cases,abnormal branch vascular network in 19 cases,and abnormal branch vascular network with characteristic polypoid lesions in 11 cases,the detection rate was 92.00%(46/50).There was no significant difference in the detection rate between the two examination methods(χ^(2)=0.709,P=0.400).Kappa consistency test showed that ICGA and OCTA had high consistency in diagnosing polypoid choroidal vascular disease(Kappa=0.816,P<0.001).The sensitivity,specificity and accuracy of OCTA in the diagnosis of polypoid choroid angiopathy were 97.83%(45/46),75.00%(3/4)and 92.00%(46/50),respectively,based on the ICGA results as the gold standard.Conclusion The consistency of ICGA and OCTA in the diagnosis of polypoid choroidal vascular disease is high.If ICGA shows abnormal branch vascular network,OCTA shows similar findings.In patients with characteristic polypoid lesions on ICGA,obvious strong signal highlights can be seen on OCTA.ICGA and OCTA showed a certain similarity in the shape and location of the lesions.
作者
罗洁
李小平
王婵婵
LUO Jie;LI Xiaoping;WANG Chanchan(Department of Functional Examination,the Affiliated Eye Hospital of Nanchang University,Jiangxi Province,Nanchang330006,China;Department of Health Management,the 908th Hospital of PLA Joint Service Support Force,Jiangxi Province,Nanchang330001,China)
出处
《中国当代医药》
CAS
2024年第2期9-13,共5页
China Modern Medicine
基金
江西省卫生健康委科技计划项目(SKJP220211166)。
