摘要
目的:探究单侧双通道内镜(UBE)下腰椎间植骨融合内固定术治疗退行性腰椎滑脱(DLS)的临床价值。方法:选取2020年3月—2023年1月江西省中西医结合医院收治的60例DLS患者,根据随机数字表法分为两组,即对照组(n=30)、观察组(n=30)。对照组进行传统手术治疗,观察组接受UBE下腰椎间植骨融合内固定术治疗。比较两组手术相关指标、疼痛程度[视觉模拟评分法(VAS)]、炎症指标[白细胞计数(WBC)、中性粒细胞计数(NE)、C反应蛋白(CRP)];随访3个月,比较椎间融合率。结果:观察组术中出血量少于对照组,住院时间短于对照组,椎间融合率高于对照组,差异均有统计学意义(P<0.05)。两组手术用时比较,差异无统计学意义(P>0.05)。术后3 d、7 d、1个月,两组VAS评分逐渐下降,且观察组均低于对照组,差异均有统计学意义(P<0.05)。术后2 d,两组WBC、NE、CRP水平均有所升高,但观察组均低于对照组,差异均有统计学意义(P<0.05)。结论:UBE下腰椎间植骨融合内固定术用于DLS患者中,可减少出血量,减轻患者术后疼痛感及炎症反应程度,提高椎间融合率。
Objective:To investigate the clinical value of unilateral biportal endoscopic(UBE)lumbar intervertebral bone graft fusion and internal fixation in the treatment of degenerative lumbar spondylolisthesis(DLS).Method:A total of 60 DLS patients admitted to Jiangxi Hospital of Integrated Traditional and Western Medicine from March 2020 to January 2023 were selected and divided into two groups according to random number table method,control group(n=30)and observation group(n=30).The control group received traditional surgery,and the observation group received UBE lumbar intervertebral bone graft fusion and internal fixation.Operation-related indexes,pain degree[visual analogue scale(VAS)],inflammatory indexes[white blood cell count(WBC),neutrophil count(NE),C reactive protein(CRP)]were compared between the two groups,the interbody fusion rate was compared after 3 months of follow-up.Result:The intraoperative bleeding volume in the observation group was less than that in the control group,and the hospital stay was shorter than that in the control group,and the interbody fusion rate was higher than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in operation time between the two groups(P>0.05).After 3 days,7 days and 1 month,VAS scores of both groups decreased gradually,and those in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).2 days after surgery,the levels of WBC,NE and CRP in both groups were increased,but those in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The use of UBE in DLS patients can reduce the bleeding volume,reduce the degree of postoperative pain and inflammation,and improve the rate of interbody fusion.
作者
胡波
陈萍
陆文杰
李思云
李耀华
周湘桂
刘虹
陈华龙
谢非
HU Bo;CHEN Ping;LU Wenjie;LI Siyun;LI Yaohua;ZHOU Xianggui;LIU Hong;CHEN Hualong;XIE Fei(Orthopedics and Traumatology Department Second,Jiangxi Hospital of Integrated Traditional and Western Medicine,Nanchang 330000,China;不详)
出处
《中国医学创新》
CAS
2024年第2期32-35,共4页
Medical Innovation of China
基金
江西省卫生健康委科技计划项目(202311239)。
关键词
退行性腰椎滑脱
单侧双通道内镜
腰椎间植骨融合内固定术
疼痛度
Degenerative lumbar spondylolisthesis
Unilateral biportal endoscopic
Lumbar intervertebral bone graft fusion and internal fixation
Pain degree
