摘要
目的 探究早泄患者各项阴茎电生理检查指标的特点与勃起功能障碍(Erectile dysfunction, ED)间的关系。方法 回顾性研究了2022年1月至2022年10月于我院门诊就诊的136例早泄(Premature ejaculation, PE)患者,采用国际勃起功能指数评分表(IIEF-5)、焦虑自评量表(Self-rating anxiety scale, SAS)和抑郁自评量表(Self-rating depression scale, SDS)对患者的勃起功能和心理状态进行评估。利用肌电图/诱发电位仪测量阴茎神经电生理各项指标。以t检验比较定量资料,Pearson相关系数比较定量资料间相关性。采用Fisher确切概率法检验定性资料,P<0.05被认为差异具有统计学意义。结果 阴茎背神经体感诱发电位(Dorsal nerve somatosensory evoked potentials, DNSEP)值异常与DNSEP值正常的患者比较,DNSEP值异常的患者SAS评分与SDS评分显著降低(t=2.727,P<0.05:t=3.17,P<0.05)。阴茎交感皮肤反应(Penile sympathetic skin responses, PSSR)值异常的患者与PSSR正常的患者比较,PSSR值异常的患者SDS评分显著低于PSSR正常的患者(t=2.347,P<0.05)。患有心理障碍的患者(焦虑和抑郁)与无心理障碍患者比较,IIEF-5评分具有显著差异,具有更严重的ED水平(t=6.649,P<0.01;t=5.172,P<0.01)。SAS、SDS评分与IIEF-5评分间呈负相关性,差异具有统计学意义(r=-0.526,P<0.01;r=-0.52,P<0.01)。电生理结果正常患者ED患病率显著高于其他组(P<0.001)。结论 电生理结果正常的PE患者,焦虑和抑郁的水平更高,阴茎敏感度更低,有更高概率合并ED,且ED的严重程度与心理因素密切相关。
Objective To explore the association between the characteristics of penile nerve electrophysiological examination and the incidence of erectile dysfunction(ED)in premature ejaculation patients.Methods Clinical data of 136 patients with PE who were treated in our hospital from January 2022 to October 2022 were retrospectively analyzed.Erectile function and psychological state of the patients were evaluated using the International Index of Erectile Function(IIEF⁃5),Self⁃Rating Anxiety Scale(SAS)and Self⁃rating Depression Scale(SDS).The electrophysiological indicators of penile nerves were measured by electromyography/evoked potential instrument.Quantitative data was compared using t test.The correlation between two quantitative data was determined using Pearson correlation coefficient.Qualitative data were compared using Fisher’s exact probability method.Results There were significant differences in SAS and SDS scores between patients with abnormal DNSEP values and normal DNSEP values(t=2.727,P<0.05:t=3.17,P<0.05),and the SAS score and SDS score of the patients with abnormal DNSEP values were all significantly lower than those of the patients with normal DNSEP values.The SDS score of patients with abnormal PSSR value was significantly lower than that of patients with normal PSSR value(t=2.347,P<0.05).The IIEF⁃5 score of anxious patients was significantly different from that of non⁃anxious patients(t=6.649,P<0.01),and the IIEF⁃5 score of depressed patients was also significantly different from that of non⁃depressed patients(t=5.172,P<0.01).The patients with anxiety and depression had more severe ED levels.SDS and SDS scores were negatively correlated with IIEF⁃5 scores(r=-0.526,P<0.01;r=-0.52,P<0.01).The prevalence of ED in patients with normal electrophysiological results was significantly higher than that in other patients(P<0.001).Conclusions Our results suggest that PE patients with normal electrophysiological results are more prone to have severe anxiety and depression,and a higher probability
作者
丁伟
宋伟杰
隆金松
何乐业
Ding Wei;Song Weijie;Long Jinsong;He Leye(Department of Urology,The Third Xiangya Hospital,Central South University,Changsha 410013,Hunan,China;Sexual Health Research Center,The Third Xiangya Hospital,Central South University,Changsha 410013,Hunan,China)
出处
《中国男科学杂志》
CAS
CSCD
2023年第6期29-33,共5页
Chinese Journal of Andrology
关键词
早泄
勃起功能障碍
阴茎
神经电生理
焦虑
抑郁
premature ejaculation
erectile dysfunction
penis
neurophysiology
anxiety
depression
