摘要
鸡的免疫性状是一种由多个微效基因调控的经济性状。随着规模化和集约化养鸡业的发展,家鸡免疫功能受环境中的病原体影响加重,传统的疾病治疗方案受限。应用分子生物学技术手段,探究家鸡的免疫相关基因的调控机制,有助于从根本上提高家鸡的免疫力。对家鸡免疫系统进行了概述,从免疫防治和疾病方向综述了TLRs、MHC、MX、IFN、NRAMP和IL等影响家鸡免疫性状的关键调控基因,旨在为家鸡抗病育种提供理论依据。
The immune trait in chickens is an economic trait regulated by several microgenes.With the development of large-scale and inten⁃sive chicken industry,the immune function of domestic chickens is more affected by the pathogens in the environment,and the traditional dis⁃ease treatment programs are limited.The application of molecular biology technology to explore the regulation mechanism of immune-related genes in domestic chickens helps to fundamentally improve the immunity of domestic chickens.This paper gives an overview of the immune sys⁃tem of domestic chickens,reviews the key regulatory genes of TLRs,MHC,MX,IFN,NRAMP,IL and so on,aiming to provide a theoretical basis for the breeding of disease resistance.
作者
曹建艳
闫世雄
张瑞芳
豆腾飞
CAO Jian-yan;YAN Shi-xiong;ZHANG Rui-fang(College of Animal Science and Technology,Yunnan Agricultural University,Kunming,Yunnan 650201)
出处
《安徽农业科学》
CAS
2024年第2期10-14,共5页
Journal of Anhui Agricultural Sciences
基金
云南省邱声祥专家工作站项目(202005AF150039)
云岭产业技术领军人才项目(YNWR-CYJS-2015-027)。
关键词
家鸡
免疫
调控基因
抗病育种
Domestic chicken
Immunity
Gene regulation
Breeding of disease resistance
