摘要
目的观察儿童眼弓蛔虫病(OT)的彩色多普勒血流显像(CDFI)特征。方法回顾性临床研究。2014年7月至2020年6月于首都医科大学附属北京同仁医院眼科经临床和实验室检测确诊的OT患者61例61只眼纳入研究。其中,男性45例45只眼,女性16例16只眼(男∶女=2.81∶1);年龄(6.93±2.50)岁。右眼、左眼分别为29、32只眼。患者双眼均行二维超声、CDFI检查。采用二维超声估测患眼及对侧健康眼眼轴长度(AL),其中采用光学生物测量仪和(或)A型超声测量AL者52例。超声检查后1周内行玻璃体视网膜手术。应用二维超声观察玻璃体内混浊形态、与眼球壁相连情况、是否发生玻璃体后脱离及视网膜脱离。应用血流显像功能观察病理膜上是否存在血流信号,统计不同形态玻璃体混浊及牵拉性视网膜脱离的检出率;分析眼内增生性病变所在位置。患眼与对侧健康眼AL比较行配对t检验。对CDFI检查及玻璃体视网膜手术中所见增生性病变位置行Kappa一致性检验。结果所有患眼均存在不同程度玻璃体混浊。其中,混浊呈典型"圣诞树样"23只眼(37.7%,23/61);团状及条状回声27只眼(44.3%,27/61);细弱点状及条状回声9只眼(14.8%,9/61);大量致密点状及条状回声2只眼(3.3%,2/61)。存在牵拉性视网膜脱离50只眼(82.0%,50/61),其中条带状回声可探及血流信号46只眼(92.0%,46/50);未见明显血流信号4只眼(8.0%,4/50)。CDFI、手术中可见眼内增生性病变分布于周边部者分别为5(8.2%,5/61)、4(6.6%,4/61)只眼;后极部者分别为18(29.5%,18/61)、14(23.0%,14/61)只眼;周边部及后极部均存在者分别为38(62.3%,38/61)、43(70.5%,43/61)只眼。CDFI、手术中对增生性病变位置检出的一致性较好(κ=0.832,95%可信区间0.691~0.973,P<0.001)。二维超声测量结果显示,患眼AL小于对侧健康眼者46例(75.4%,46/61)。行AL生物测量的52例,患眼AL较对侧健康眼短(0.63±0.68)mm,差异有统计学意义(t=-
ObjectiveTo summarize the characteristics of color doppler flow imaging(CDFI)of ocular toxocariasis(OT)in children.MethodsA retrospective clinical study.From July 2014 to June 2020,61 OT patients with 61 eyes diagnosed through clinical and laboratory testing in the Department of Ophthalmology of Beijing Tongren Hospital of Capital Medical University were included in the study.There were 45 males with 45 eyes and 16 females with 16 eye(male:female=2.81:1).Age were(6.93±2.50)years.The right eye and left eye were 29 and 32 eyes,respectively.Both eyes of the patient underwent two-dimensional ultrasound and CDFI examination.Two dimensional ultrasound was used to estimate the axial length(AL)of the affected eyes and healthy eyes on the opposite side.Among them,52 cases were measured for AL using optical biometry and/or A-mode ultrasound.Vitreoretinal surgery was performed within one week after ultrasound examination.Two-dimensional ultrasound was used to observe the morphology of vitreous opacity,its connection to the eyeball wall,and whether posterior vitreous detachment and retinal detachment have occurred.CDFI examination was used to observe the presence of blood flow signals on the pathological membrane.The detection rates of different forms of vitreous opacity and traction retinal detachment were calculated.The location of proliferative lesions in the eye was analyzed.Paired t-test was performed to compare the AL of the affected eye and the healthy eye on the opposite side.Perform Kappa consistency test on the location of proliferative lesions was used during CDFI examination and vitreoretinal surgery.ResultsAll affected eyes have varying degrees of vitreous opacity.Among them,23 eyes(37.7%,23/61)showed typical"Christmas tree"like turbidity;27 eyes(44.3%,27/61)had clustered and striped echoes;9 eyes(14.8%,9/61)had weak punctate and strip echoes.Two eyes(3.3%,2/61)showed a large amount of dense punctate and strip-shaped echoes.There were 50 eyes(82.0%,50/61)with traction retinal detachment,of which 46 eyes(92.0%,4
作者
陈伟
杨文利
刘敬花
李栋军
王子杨
赵琦
李逸丰
崔蕊
沈琳
刘倩
Chen Wei;Yang Wenli;Liu Jinghua;Li Dongjun;Wang Ziyang;Zhao Qi;Li Yifeng;Cui Rui;Shen Lin;Liu Qian(Beijing Tongren Eye Center,Beijing Ophthalmology&Visual Sciences Key Laboratory,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
出处
《中华眼底病杂志》
CAS
CSCD
北大核心
2024年第1期39-43,共5页
Chinese Journal of Ocular Fundus Diseases
