摘要
目的分析心房颤动(房颤)患者左心耳发育不良的临床及影像学特点,探讨其预防左心房血栓抗凝方案。方法回顾性研究2018年7月至2023年10月上海健康医学院附属周浦医院经左心房电子计算机断层扫描造影成像(CTV)和(或)经食管超声心动图(TEE)检查发现左心耳发育不良的房颤患者5例,分析其临床特征、影像学资料、抗凝治疗方案。结果5例房颤患者,1例完成左心房CTV及TEE检查,1例完成胸部CT平扫及TEE检查,3例完成左心房CTV检查。5例患者均依靠左心房CTV延迟期及肺静脉期多平面重建和(或)TEE结果诊断左心耳发育不良,TEE可见细小的左心耳间隙或不能见到左心耳口。左心耳发育不良均表现为左心耳小,左心耳壁肥厚,无左心耳腔或左心耳腔细小,左心房CTV对比剂难以进入。5例患者均合并心脑血管动脉粥样硬化,1例行冷冻消融术,既有抗血小板方案也有抗凝方案或二者兼有。结论左心房CTV延迟期及肺静脉期多平面重建可明确诊断特殊类型的发育不良的左心耳,TEE对诊断有一定辅助作用。伴左心耳发育不良的房颤患者抗凝方案有待进一步认识。
Objective This study aims to analyze the clinical and imaging characteristics of atrial fibrillation(AF)patients with left atrial appendage(LAA)hypoplasia and to explore the effectiveness of anticoagulation in preventing left atrial thrombus.Methods A retrospective analysis was conducted on five AF patients with LAA hypoplasia.The patients in this study were diagnosed using left atrial computed tomography venography venography(CTV)and/or transesophageal echocardiography(TEE)out of a total of 3068 patients who were admitted to Zhoupu hospital between July 2018 and October 2023.The analysis included an examination of clinical features,and imaging data,and anticoagulation treatment was analyzed.Results The study found that out of the 5 patients with LAA hypoplasia,only one patient underwent both left atrial CTV and TEE examinations.One patient underwent chest CT scan and TEE,while the remaining three patients underwent complete left atrial CTV and were all diagnosed with LAA hypoplasia.The diagnosis relied on the delay and venous phase of multiplanar reconstruction of left atrial CTV,while TEE was only able to detect small crevices or no abnormalities.The incidence of LAA hypoplasia was 1.63‰.The characteristics of LAA hypoplasia include a small LAA,thick LAA wall,and LAA without cavity or small.All five AF patients were complicated with cardio-cerebrovascular atherosclerosis,one patient underwent cryoablation,and and antiplatelet or anticoagulant regimen or both therapy strategy was selected.Conclusions LAA hypoplasia is a unique subtype of LAA,that can be diagnosed through multi-plane reconstruction in the delayed and venous phase of left atrial CTV.TEE can serve as a supplementary diagnostic tool,and further research is needed to determine the anticoagulation regimen for AF patients with LAA hypoplasia.
作者
袁明远
李炜
郇强
宁忠平
赵志宏
YUAN Ming-yuan;LI Wei;HUAN Qiang;NING Zhong-ping;ZHAO Zhi-hong(Department of Radiology,Department of Cardiology,Zhoupu Hospital Affiliated to Shanghai Health Medical College,Shanghai 201318,China;不详)
出处
《中国介入心脏病学杂志》
CSCD
2023年第12期921-928,共8页
Chinese Journal of Interventional Cardiology
基金
上海市浦东新区高峰学科建设基金项目(PWYgf2021-04)
上海市浦东新区新兴交叉学科建设项目(PWXx2020-06)
杭州市重点学科心血管内科学建设基金项目(HZ202014)。
关键词
左心耳发育不良
心房颤动
电子计算机断层扫描造影成像
经食管超声心动图
抗凝治疗
Left atrial appendage hypoplasia
Atrial fibrillation
Computed tomography venography
Transesophageal echocardiography
Anticoagulant therapy
