摘要
目的探究苍附导痰汤结合腹针治疗痰湿型多囊卵巢综合征的疗效观察。方法选取我院2020年1月—2022年1月收治的80例多囊卵巢综合征患者为研究对象。采用随机分组法分为观察组与对照组,两组各40例患者,对照组采用达英-35治疗,观察组在此基础上联合使用苍附导痰汤结合腹针治疗。观察两组患者治疗前后卵泡刺激素(follicle stimulating hormone,FSH)、黄体生成素(luteinizing hormone,LH)、雌二醇(estradiol,E_(2))、睾酮(testosterone,T)及催乳素(prolactin,PRL)。卵巢阻力指数(resistance index,RI)、卵巢搏动指数(pulsitility index,PI)、卵泡数目(FN)及糖脂代谢情况。观察两组患者临床疗效与不良反应发生率。结果两组患者治疗前FSH、LH、E_(2)、T、PRL水平与治疗后两组患者FSH、PRL、E_(2)水平差异无统计学意义(P>0.05)。治疗后观察组LH、T水平较对照组显著降低(P<0.05)。两组患者治疗前RI、PI、FN水平差异无统计学意义,且治疗后两组患者PI水平差异无统计学意义(P>0.05)。治疗后观察组RIR、FN水平较对照组显著降低(P<0.05)。两组患者治疗前FINS、ISI、HOMA-IR水平差异无统计学意义(P>0.05)。治疗后观察组FINS、HOMA-IR水平较对照组显著降低,且ISI较对照组显著升高(P<0.05)。观察组临床总有效率为92.50%(37/40)显著高于对照组72.50%(29/40)(χ^(2)=5.541,P=0.018)。观察组总不良反应发生率为7.50%(3/40)略低于对照组10.00%(4/40),但两组患者总不良发应发生率差异无统计学意义(χ^(2)=0.156,P=0.692)。结论苍附导痰汤结合腹针治疗能有效降低糖脂代谢指标和性激素指标,改善卵巢超声异常情况,提高患者临床疗效及降低不良反应发生率。
Objective To observe the clinical effect of Cangfu Daotan Decoction(苍附导痰汤)combined with abdominal acu-puncture in the treatment of polycystic ovary syndrome of phlegm-damp type.Methods Eighty patients with polycystic ovary syn-drome in the hospital from January 2020 to January 2022 were enrolled and randomly divided into two groups,each with 40 cases.The control group received diane-35 treatment.Based on this,the observation group received Cangfu Daotan Decoction combined with abdominal acupuncture.The parameters including follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E_(2)),testosterone(T)and prolactin(PRL),ovarian resistance index(RI),ovarian pulsatility index(PI),follicles number(FN)and glycolipid metabolism were observed in both groups.Thereafter,the clinical efficacy and adverse reaction rate were compared between two groups.Results The levels of FSH,E_(2)and PRL yielded no statistical difference between two groups before and after treatment(P>0.05),while the levels of LH and T were notably decreased in the observation group compared with those of the control group after treatment(P<0.05).No statistical difference was found in RI,PI or FN between two groups before treatment(P>0.05).The post-treatment PI values showed no difference between two groups(P>0.05),while the values of RI and FN of the observation group were obviously lower than those of the control group(P<0.05).The metabolic markers fasting insulin(FINS),insulin sensitivity index(ISI)and homeostasis model assessment of insulin resistance(HOMA-IR)denoted no statisti-cal difference between two groups before treatment(P>0.05).After treatment,the observation group had decreased values of FINS and HOMA-IR and increased ISI value compared with the control group,with statistical difference(all P<0.05).The clinical efficacy rate was 92.50%(37/40)in the observation group,which was notably higher than 72.50%(29/40)in the con-trol group,with statistical difference(χ^(2)=5.541,P=0.018).The adverse reaction rate was 7.50%(3/40)i
作者
毕富玺
吴林玲
张晗
闫颖
BI Fuxi;WU Linling;ZHANG Han;YAN Ying(Department of Gynecology,The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300193,China)
出处
《辽宁中医杂志》
2023年第11期88-91,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
全国中医学术流派传承工作室项目(LPGZS2012-04)
天津教委科研计划项目(2018KJ019)。
关键词
苍附导痰汤
腹针
多囊卵巢综合征
睾酮
糖脂代谢
Cangfu Daotan Decoction(苍附导痰汤)
abdominal acupuncture
polycystic ovary syndrome
testosterone
glyco-lipid metabolism
