摘要
自2014年发现超高剂量率闪光放射治疗(Flash-RT)对正常组织的保护效应以来,得到了放射治疗学科的广泛关注。超高剂量率Flash-RT的研究需求对现有的放射治疗设备提出了新的挑战。本综述从X射线Flash-RT的研究和临床应用需求出发,分析Flash-RT对设备提出的新需求,介绍目前具备X射线Flash-RT实验能力的科研设施,以及正在开发的专用Flash-RT设备的情况。Flash-RT机制的研究需要现有高能X射线源设备向大功率方向发展,而Flash-RT的临床应用要求这些瞬态大功率装置具备多角度照射、适形放射治疗等放射治疗技术。目前,我国对X射线Flash-RT装置的研究处于世界前列,有望在X射线Flash-RT领域实现高端医疗设备的率先突破。
The protection effect of flash-radiotherapy(Flash-RT)with super-high dose on normal tissue has obtained wide attention in therapeutic radiology since it was found in 2014 year.The increasing research demand of Flash-RT with super-high dose-rate proposed new challenge for the existing radiotherapy equipment.Based on the demands of FLASHRT research and clinical application,this review analyzed the proposed new requirement of Flash-RT for equipment,and introduce current scientific facilities with the experimental ability of X-ray FLASH-RT,as well as the situation of the specialized FLASH-RT equipment which were developing.The research of Flash-RT mechanism need the existing equipment with high-energy X-ray source develop toward high power,while the clinical application of Flash-RT demand these transient high-power devices should possess a series of radiotherapy techniques such as multi angle irradiation,conformal radiotherapy and others.Currently,China’s X-ray FLASH-RT research is at the forefront of the world,which is expected to achieve the first breakthrough of high-end medical equipment in the X-ray Flash RT field.
作者
唐若
何小中
朱鹏飞
张卓
黄子平
廖树清
魏涛
杨柳
石金水
Tang Ruo;He Xiaozhong;Zhu Pengfei;Zhang Zhuo;Huang Ziping;Liao Shuqing;Wei Tao;Yang Liu;Shi Jinshui(Institute of Fluid Physics,China Academy of Engineering Physics,Mianyang 621900,China)
出处
《中国医学装备》
2024年第1期24-28,共5页
China Medical Equipment
