摘要
目的:分析腹膜透析相关性腹膜炎(PDAP)的中医证型的分布规律及PDAP的影响因素。方法:回顾性选取244例腹膜透析患者作为研究对象,根据是否发生腹膜炎分为腹膜炎组74例和无腹膜炎组170例。比较2组一般资料、实验室指标;分析腹膜炎组PDAP中医证型分布规律及PDAP发生影响因素。结果:2组年龄、性别、腹透龄、体质量指数(BMI)、合并糖尿病比较,差异无统计学意义(P>0.05)。腹膜炎组文化程度低于无腹膜炎组(P<0.05),腹膜炎组血清铁蛋白(TRF)水平高于无腹膜炎组(P<0.05),白蛋白(Alb)水平低于无腹膜炎组(P<0.05)。腹膜炎组中腹透液致病菌培养常见于肺炎克雷伯菌、唾液链球菌;常见诱因有非正规消毒或接触不良、胃肠功能紊乱、呼吸道感染等。临床PDAP本虚证以脾肾气虚证、脾肾阳虚证多见,标实证以湿浊证为主。多因素Logistics回归分析显示,高文化程度、Alb为PDAP发生的保护因素,高TRF为PDAP发生的危险因素。结论:临床上PDAP本虚证以脾肾气虚证和脾肾阳虚证为主,标实证以湿浊证为主。高文化程度、Alb为PDAP发生的保护因素,高TRF为PDAP发生的危险因素。
Objective:To analyze the distribution rules of traditional Chinese medicine syndrome(TCM)types of peritoneal dialysis-associated peritonitis(PDPA)and the influencing factors of PDPA.Methods:A total of 244 patients who received peritoneal dialysis were retrospectively selected as the study objects,and divided into the peritonitis group and the non-peritonitis group according to whether PDPA occurred,with 74 and 170 cases in each group,respectively.The general data and laboratory indexes were compared between the two groups;the distribution rules of TCM syndrome types and influencing factors of PDPA in the peritonitis group were analyzed.Results:There was no significant difference being found in the comparisons of age,gender,the age of receiving peritoneal dialysis,body mass index(BMI)and complicated with diabetes between the two groups(P>0.05).The level of education in the peritonitis group was higher than that in the non-peritonitis group(P<0.05),the level of serum transferrin(TRF)was higher than that in the non-peritonitis group(P<0.05),and the level of albumin(Alb)was lower than that in the non-peritonitis group(P<0.05).In the pathogenic bacteria culture of peritoneal dialysis fluid in the peritonitis group,Klebsiella pneumoniae and Streptococcus salivarius were commonly seen;the common causes were irregular disinfection or poor contact,gastrointestinal dysfunction,respiratory tract infection,etc.The syndrome of deficiency in origin of clinical PDPA mainly includes the syndrome of spleen-kidney deficiency and syndrome of spleen-kidney yang deficiency,and the syndrome of excess in superficiality is usually the syndrome of dampness turbidity.Multifactorial logistic regression analysis showed that the high level of education and Alb were protective factors for the occurrence of PDAP,and high TRF was a risk factor.Conclusion:In clinical,the syndrome of deficiency in origin of PDPA mainly includes the syndrome of spleen-kidney deficiency and syndrome of spleen-kidney yang deficiency,and the syndrome of excess in sup
作者
李超民
徐娟
李燕林
LI Chaomin;XU Juan;LI Yanlin(Department of Nephrology,Zhongshan Hospital of Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine,Zhongshan Guangdong 528401,China;Department of Nephrology,Zhongshan Hospital of Chinese Medicine,Zhongshan Guangdong 528401,China)
出处
《新中医》
CAS
2023年第23期96-100,共5页
New Chinese Medicine
基金
广东省中医药局科研专项研究课题(20223020)
中山市卫生局课题(2021J182)
国家临床重点专科(肾脏病)建设项目(粤财社〔2014〕80号)。
关键词
腹膜透析相关性腹膜炎
中医证型
影响因素
文化程度
白蛋白
铁蛋白
Peritoneal dialysis-associated peritonitis
Traditional Chinese medicine syndrome types
Influencing factors
Level of education
Albumin
Transferrin
