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鼻咽癌放疗后吞咽障碍患者不同部位最大舌压与口咽期活动的相关性研究

Correlation between maximum tongue pressure and oropharyngeal activity in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma
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摘要 目的通过观察鼻咽癌放疗后吞咽障碍患者的最大舌压值和口咽期吞咽造影,探讨此类患者的舌前、舌中、舌后最大压力与口咽期吞咽功能的相关性。方法共纳入19例鼻咽癌放疗后吞咽障碍患者作为研究对象,采用新型柔性九位点舌压传感器测量患者舌体前、中、后三个部位的最大舌压值,随后进行吞咽造影检查,量化分析口腔运送时间、食道上括约肌(UES)开放持续时间和UES开放幅度等指标。分析舌前、舌中及舌后最大压力值与口腔运送时间、UES开放持续时间及UES开放幅度间的相关性。结果舌中、舌后最大压力值与口腔运送时间具有显著负相关性(P<0.05),舌前最大压力值与口腔运送时间无显著相关性(P>0.05);舌前、舌中、舌后最大压力值与UES开放持续时间、UES开放幅度均存在显著正相关性(P<0.05)。结论舌前、舌中及舌后最大压力值均与鼻咽癌放疗后吞咽障碍患者口咽期的活动功能高度相关。 Objective To observe the maximum tongue pressure and study the oropharyngeal activity during swallowing of patients with nasopharyngeal carcinoma(NPC)after radiotherapy so as to correlate the maximum tongue pressure with swallowing function.Methods The mean maximum tongue pressure of nineteen NPC patients with dysphagia was measured at the anterior(TA),middle(TM)and posterior(TP)positions,followed by video fluo-roscopy.Oral transit time(OTT),upper esophageal sphincter(UES)opening time(UOT)and UES opening range(UOR)were correlated with the mean maximum tongue pressures.Results The maximum pressure at the TM and TP positions was significantly negatively correlated with OTT,but there was no significant correlation with the anterior readings.The maximum pressures at all three tongue positions were,however,positively correlated with UOT and UOR.Conclusion The maximum pressure at the TA,TM and TP positions is strongly correlated with the swallo-wing function of NPC patients.
作者 赵妃 吾米提·艾海提 孙思明 张耀文 谢纯青 杨晨 窦祖林 唐志明 Zhao Fei;Wu Mi Ti·Ai Hai Ti;Sun Siming;Zhang Yaowen;Xie Chunqing;Yang Chen;Dou Zulin;Tang Zhiming(Department of Rehabilitation Medicine,The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Rehabilitation Medicine,Yuedong Hospital,The Third Affiliated Hospital of Sun Yat-sen University,Meizhou 514000,China;Department of Rehabilitation Medicine,Guangdong Yanling Hospital,Guangzhou 510507,China)
出处 《中华物理医学与康复杂志》 CSCD 北大核心 2023年第12期1073-1077,共5页 Chinese Journal of Physical Medicine and Rehabilitation
基金 国家自然科学基金项目(81401872) 广东省医学科研基金项目(A2022240,B2023071) 中山大学附属第三医院粤东医院院内基金项目(YDN2022002)。
关键词 鼻咽癌 吞咽困难 最大舌压值 吞咽造影 Nasopharyngeal carcinoma Dysphagia Tongue pressure Videofluoroscopy
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