摘要
BACKGROUND Surgical site infections(SSIs)increase mortality,hospital stays,additional medical treatment,and medical costs.Subcutaneous drains prevent SSIs in gynecological and breast surgeries;however,their clinical impact in abdominal surgery remains unclear.AIM To investigate whether subcutaneous drains were beneficial in abdominal surgery using a systematic review and meta-analysis.METHODS The database search used PubMed,MEDLINE,and the Cochrane Library.The following inclusion criteria were set for the systematic review:(1)Randomized controlled trial studies comparing SSIs after abdominal surgery with or without subcutaneous drains;and(2)Studies that described clinical outcomes,such as SSIs,seroma formation,the length of hospital stays,and mortality.RESULTS Eight studies were included in this meta-analysis.The rate of total SSIs was significantly lower in the drained group(54/771,7.0%)than in the control group(89/759,11.7%),particularly in gastrointestinal surgery.Furthermore,the rate of superficial SSIs was slightly lower in the drained group(31/517,6.0%)than in the control group(49/521,9.4%).No significant differences were observed in seroma formation between the groups.Hospital stays were shorter in the drained group than in the control group.CONCLUSION Subcutaneous drains after abdominal surgery prevented SSIs and reduced hospital stays but did not significantly affect seroma formation.The timing of drain removal needs to be reconsidered in future studies.
基金
Supported by Grants-in-Aid from JSPS KAKENHI,No.JP 21K10715 and No.JP 20K10404
Northern Advancement Center for Science&Technology,No.T-2-2
the Yasuda Medical Foundation,No.31010316
the Okawa Foundation for Information and Telecommunications,No.41111042
Taiju Life Social Welfare Foundation,No.50811490
Japan Keirin Autorace Foundation,No.2023M-378
Project Mirai Cancer Research Grants,No.31010269
Takahashi Industrial and Economic Research Foundation,No.50411278
Sapporo Doto Hospital,No.50311211
Noguchi Hospital,No.40310551
Doki-kai Tomakomai Hospital,No.40710739
Tsuchida Hospital,No.50811478.