摘要
2型糖尿病(T2DM)是一种慢性代谢性疾病,其主要危害在于慢性并发症,在长期高血糖刺激下,患者的心脏、肾脏、眼睛等器官均会发生病变,严重危害身体健康。尿白蛋白/肌酐比值(UACR)是反映肾损伤的敏感指标,与传统尿白蛋白或尿肌酐相比更能准确评估肾功能。UACR不仅可用于糖尿病肾病的评估,与糖尿病视网膜病变、认知功能障碍、非酒精性脂肪性肝病等T2DM慢性并发症也存在一定相关性,可在一定程度上影响疾病的发生发展过程。因此,深入研究UACR与T2DM慢性并发症的关系,可以为相关疾病的治疗提供新思路。
Type 2 diabetes mellitus(T2DM)is a chronic metabolic disease,the main harm of which lies in chronic complications.Under the stimulation of long-term hyperglycemia,the heart,kidney,eyes and other organs of patients will undergo pathological changes,seriously endangering their health.Urinary albumin to creatinine ratio(UACR)is a sensitive indicator of renal injury and can more accurately evaluate renal function than traditional urinary albumin or creatinine.UACR not only can be used to assess diabetic nephropathy,but also has some connection with other T2DM chronic complications such as diabetic retinopathy,cognitive dysfunction,nonalcoholic fatty liver disease,and can affect the occurrence and development of the above diseases to a certain extent.Therefore,in-depth studies on the relationship between UACR and chronic complications of T2DM can provide new ideas for the treatment of related diseases.
作者
崔健
夏青
周茜宁
CUI Jian;XIA Qing;ZHOU Xining(Department of Clinical Laboratory,Beijing Traditional Chinese Medical District,Chinese PLA General Hospital,Beijing 100120,China;Medical Laboratory Center,Chinese PLA General Hospital,Beijing 100853,China)
出处
《医学综述》
CAS
2023年第24期5765-5768,5773,共5页
Medical Recapitulate
关键词
糖尿病
2型
慢性并发症
尿白蛋白
尿肌酐
Diabetes mellitus,type 2
Chronic complications
Urinary albumin
Urinary creatinine
