摘要
目的 探讨卡前列甲酯栓和米索前列醇片在绝经后妇女宫内节育环取出中的疗效对比。方法 方便选取2014年12月—2016年12月莆田市计划生育服务站收治的宫内节育环取出绝经后妇女86例作为研究对象,依据随机数表法分为对照组(n=43)和观察组(n=43)。对照组予以卡前列甲酯栓治疗,观察组给予米索前列醇片治疗。比较两组患者疼痛程度、宫颈管软化程度、取环效果及不良发应发生率。结果 治疗后观察组视觉模拟疼痛量表评分为(2.07±0.17)分,低于对照组的(3.62±0.43)分,差异有统计学意义(t=8.432,P<0.05)。治疗后观察组生活质量简表评分为(80.43±2.17)分,高于对照组的(70.84±1.31)分,差异有统计学意义(t=6.533,P<0.05)。治疗后观察组取环成功率为97.67%,高于对照组的90.69%,差异有统计学意义(P<0.05);观察组宫颈管软化率为97.67%,高于对照组的86.05%,差异有统计学意义(P<0.05)。两组患者用药期间不良反应发生率比较,差异无统计学意义(P>0.05)。结论 卡前列甲酯栓和米索前列醇片用于绝经后妇女宫内节育环取出患者中均可获得良好的效果,但是后者效果最佳,可有效缓解疼痛程度,提高生活质量,取环效果好,且未产生严重不良反应。
Objective To explore the comparative efficacy of Carboprost Methylate Suppositorites and Misoprostol Tablets in removing intrauterine contraceptive device in postmenopausal women.Methods A total of 86 postmenopausal women with intrauterine device removed from Putian Family Planning Service Station from December 2014 to December 2016 were conveniently selected as the study objects,and divided into control group(n=43) and observation group(n=43) according to random number table method.The control group was treated with carprost methyl ester suppository,and the observation group was treated with Misoprostol Tablets.The degree of pain,the degree of cervical malacia,the effect of ring extraction and the incidence of adverse reactions were compared between the two groups.Results After treatment,the Visual Analogue Pain Score in the observation group was(2.07±0.17) points,lower than that in the control group(3.62±0.43) points,and the difference was statistically significant(t=8.432,P<0.05).After treatment,the Mos 36-item Short From Health Survey in the observation group was(80.43±2.17) points,which was higher than that in the control group(70.84±1.31) points,and the difference was statistically significant(t=6.533,P<0.05).After treatment,the success rate of loop extraction in observation group was 97.67%,which was higher than that in control group(90.69%),the difference was statistically significant(P<0.05).The cervical duct malacia rate in observation group was 97.67%,which was higher than that in control group(86.05%),and the difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Both carprost methyl ester suppositories and misoprostol tablets can achieve good results in the removal of intrauterine devices in postmenopausal women,but the latter has the best effect,which can effectively relieve pain and improve quality of life,and has good ring removal effect without serious adverse reactions.
作者
陈秋铅
蔡健强
王素娇
CHEN Qiuqian;CAI Jianqiang;WANG Sujiao(Family Planning Technical Service Department,Putian Maternal and Child Health Hospital,Putian,Fujian Province,351100 China)
出处
《中外医疗》
2023年第31期86-89,共4页
China & Foreign Medical Treatment
关键词
卡前列甲酯栓
米索前列醇片
绝经
宫内节育环
Carboprost Methylate Suppositorites
Misoprostol Tablets
Menopause
Intrauterine contraceptive device
