摘要
[目的]分析石家庄市肿瘤登记地区2019年肺癌发病、死亡特征及2014—2019年变化趋势,为石家庄市肺癌防治工作提供依据。[方法]采用Excel 2007和SPSS 21.0按照不同性别、地区、年龄组分别计算肺癌发病率、死亡率、标化发病率、标化死亡率、0~74岁累积发病率和0~74岁累积死亡率。利用Joinpoint 4.9.0.0软件计算发病率和死亡率年度变化百分比(annual percentage change,APC)。[结果]2019年石家庄市新发肺癌病例2406例,占全部恶性肿瘤的20.12%,发病粗率、中标率和世标率分别为50.79/10万、31.03/10万和32.65/10万,0~74岁累积发病率为4.24%;肺癌死亡1976例,占全部恶性肿瘤死亡的27.94%,肺癌死亡粗率、中标率和世标率分别为41.71/10万、23.52/10万和23.37/10万,0~74岁累积死亡率为2.61%。肺癌发病和死亡均居恶性肿瘤首位。肺癌发病和死亡均随年龄增长而上升,肺癌发病在45岁以后快速上升,75~79岁年龄组达到高峰(241.90/10万),85岁及以上组肺癌发病率回落至184.96/10万;肺癌死亡45岁以后增长明显,肺癌死亡率从45~49岁组的11.79/10万上升至85岁及以上组的424.44/10万。2014—2019年石家庄市肺癌标化发病率和标化死亡率均呈下降趋势(APC=-4.17%,P=0.022;APC=-4.56%,P=0.001)。分性别、城乡统计,男性、农村肺癌发病中标率分别以每年5.62%和7.99%的趋势在下降(P均<0.05);男性、女性、城市和农村肺癌死亡中标率分别以每年3.55%、6.32%、4.57%和4.84%的趋势在下降(P均<0.05)。[结论]2014—2019年石家庄市肺癌发病和死亡呈下降趋势,但仍属于石家庄市高发癌种,男性、老年人是肺癌防治重点人群,农村是肺癌防治重点地区。
[Purpose]To analyze the incidence and mortality of lung cancer in Shijiazhuang in 2019,and to analyze its trend from 2014 to 2019.[Methods]The crude incidence and mortality rates,the age-standardized rates of the Chinese population(ASIRC,ASMRC),the age-standar-dized rates of the world population(ASIRW,ASMRW),0~74 years old cumulative incidence and mortality rates were calculated using Excel 2007 and SPSS 21.0.The annual percentage change(APC)was analyzed by Joinpoint Regression Program 4.9.0.0.[Results]In 2019,there were 2406 new cases of lung cancer in Shijiazhuang,accounting for 20.12%of all new cancer cases.The crude incidence rate of lung cancer was 50.79/105,with the ASIRC of 31.03/105 and ASIRW of 32.65/105.The cumulative incidence rate(0~74 years old)was 4.24%.There were 1976 deaths from lung cancer,accounting for 27.94%of all cancer deaths.The crude mortality rate was 41.71/105,with the ASMRC of 23.52/105 and ASMRW of 23.37/105.The cumulative mortality rate(0~74 years old)was 2.61%.The incidence and death of lung cancer ranked first among all malignant tumors.The incidence and mortality rates showed an increasing trend by age,the incidence of lung cancer increased rapidly after the age of 45 years old,reaching a peak of 241.90/105 at the age group of 75~79 years old;the mortality rate increased rapidly after the age of 45 years old,from 11.79/105 at the age group of 45~49 years old to 424.44/105 at the age group of 85+years old.The ASIRC and ASMRC showed an decreasing trend from 2014 to 2019(APC=-4.17%,P=0.022;APC=-4.56%,P=0.001).The ASIRC in male and in rural areas from 2014 to 2019 was significantly decreased with APC of-5.62%and-7.99%(P<0.05),respectively.The ASMRC of lung cancer in male,female,urban and rural areas from 2014 to 2019 was significantly decreased with APC of-3.55%,-6.32%,-4.57%and-4.84%(all P<0.05),respectively.[Conclusion]The incidence and mortality rates of lung cancer rank first among all malignant tumors in Shijiazhuang City,which showed a decreased trend from 2014 to 2019.Males and
作者
党静
马新颜
段宇帆
DANG Jing;MA Xinyan;DUAN Yufan(Shijiazhuang Center for Disease Control and Prevention,Shijiazhuang 050011,China)
出处
《中国肿瘤》
CSCD
北大核心
2023年第12期891-898,共8页
China Cancer
基金
河北省医学科学研究重点课题计划项目(20191497)。
关键词
肺癌
流行病学
发病率
死亡率
河北
lung cancer
epidemiology
incidence
mortality
Hebei
