摘要
目的:分析经颅磁刺激(TMS)联合早期介入丹佛康复训练(ESDM)在孤独症患儿中的应用效果。方法:选择2018年10月-2021年9月在九江市第一人民医院康复医院接受治疗的86例孤独症患儿,年龄2~5岁,平均年龄(4.10±0.34)岁。按随机数字表法分为两组,每组各43例。观察组中有男性22例,女性21例;平均年龄(4.10±0.34)岁;孤独症儿童行为量表(ABC)平均评分(83.12±11.92)分。对照组中有男性25例,女性18例;平均年龄(4.07±0.32)岁;ABC平均评分(82.64±11.09)分。两组均进行常规康复干预,对照组采用TMS治疗,观察组采用TMS联合ESDM治疗。比较两组的孤独症治疗评估表(ATEC)评分、ABC评分、发育商(DQ)评分、儿童孤独症评定量表(CARS)评分。结果:治疗6个月后,观察组的ATEC评分为(82.01±14.72)分、ABC评分为(62.47±8.79)分、CARS评分为(25.84±6.82)分,均低于对照组的(90.17±16.33)分、(68.14±9.20)分、(29.71±6.99)分;DQ评分为(78.39±12.43)分,高于对照组的(71.08±11.69)分,差异均有统计学意义(均P<0.05)。结论:孤独症患儿采用TMS联合ESDM治疗是可行的,可纠正患儿的异常行为,改善患儿认知、沟通及社交能力,促进患儿心理及神经发育。
Objective:To analyze the application effect of transcranial magnetic stimulation(TMS)combined with early intervention Denver rehabilitation training in children with autism.Methods:A total of 86 autistic children aged 2-5 years with an average age of(4.10±0.34)years were selected from October 2018 to September 2021 in Rehabilitation Hospital of Jiujiang First People’s Hospital.They were divided into two groups with 43 cases each according to random number table method.In the observation group there were 22 male cases and 21 female cases;the average age was(4.10±0.34)years;the average score of autism behavior checklist(ABC)of the children with autism was(83.12±11.92).In the control group there were 25 male cases and 18 female cases;the average age was(4.07±0.32)years;the average score of ABC was(82.64±11.09).Both groups received routine rehabilitation intervention,the control group was treated with TMS,the observation group was treated with TMS combined with early intervention Denver rehabilitation training.The scores of autism treatment evaluation checklist(ATEC),ABC,developmental quotient(DQ)and children autism rating scale(CARS)were compared between the two groups.Results:After 6 months of treatment,the ATEC score,ABC score and CARS score were(82.01±14.72)points,(62.47±8.79)and(25.84±6.82)points in the observation group,which were lower than those in the control group(90.17±16.33)points,(68.14±9.20)points,(29.71±6.99)points;DQ score was(78.39±12.43)points in the observation group,which was higher than(71.08±11.69)points in the control group,and the difference was statistically significant(P<0.05).Conclusion:TMS combined with early intervention Denver rehabilitation training is feasible for children with autism,which can correct abnormal behavior,improve cognition,communication and social ability,and promote psychological and neurological development of children with autism.
作者
梅连连
胡雅佩
黄也
MEI Lianian;HU Yapei;HUANG Ye(Children’s Rehabilitation Center of Rehabilitation Hospital of Jiujiang First People’s Hospital,Jiujiang,Jiangxi Province 332000,China)
出处
《上海医药》
CAS
2023年第24期41-43,53,共4页
Shanghai Medical & Pharmaceutical Journal
关键词
孤独症
儿童
经颅磁刺激
早期介入丹佛康复训练
发育商
autism
children
transcranial magnetic stimulation
early intervention Denver rehabilitation training
development quotient
