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自膨胀式经导管主动脉瓣置换术瓣膜的优势及相关研究进展

Advantages and related developments of self-expandable valves for transcatheter aortic valve replacement
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摘要 经导管主动脉瓣置换术是目前治疗主动脉瓣狭窄的有效手段,特别是对于高龄、外科高危以及不能耐受外科手术的重度主动脉瓣狭窄患者。自膨胀式瓣膜在设计及功能经过几代更新后,在治疗二叶式主动脉瓣畸形、外科生物瓣衰败及小瓣环的主动脉瓣狭窄患者中都显示出了显著的效果,同时耐久性方面也有着良好的优越性,这些良好的血流动力学结局都能转化为临床终点获益。该文通过回顾文献总结了自膨胀式瓣膜在经导管主动脉瓣置换术中的应用优势以及最新进展。 Transcatheter aortic valve replacement is an effective treatment for aortic stenosis currently,especially in elderly,surgical high-risk,and surgical procedures-intolerant patients with severe aortic stenosis.After several generations of updates in design and function,the self-expandable valves have shown significant efficacy in treating aortic stenosis patients with bicuspid aortic valve,bioprosthetic valve failure or small annulus,and superiority in terms of valve durability,and the favorable hemodynamic outcomes could translate into clinical endpoint benefit.This literature review summarizes the advantages and recent advances of the self-expandable valves in transcatheter aortic valve replacement.
作者 马云龙 吴岳 袁祖贻 韩克 MA Yunlong;WU Yue;YUAN Zuyi;HAN Ke(Department of Cardiology,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an,Shaanxi 710061,P.R.China)
出处 《华西医学》 CAS 2023年第12期1914-1919,共6页 West China Medical Journal
基金 国家自然科学基金(92049203) 国家重点研发计划(2021YFA1301200)。
关键词 经导管主动脉瓣置换术 自膨胀式瓣膜 球囊扩张式瓣膜 Transcatheter aortic valve replacement self-expandable valves balloon-expandable valves
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