摘要
糖尿病视网膜病变(DR)是导致糖尿病患者失明的主要原因,早诊断和早治疗对提高DR患者的生活质量至关重要。脉络膜血管指数(CVI)是脉络膜管腔面积与总面积的比值,可以反映脉络膜结构及血流的情况,被用于各种眼部疾病脉络膜情况的评估。CVI在DR的预测、早期干预、病情评估、预后判断等方面展现出巨大潜力。CVI与光感受器之间的联系仍有待深入研究,甚至可将CVI作为光感受器健康和视力预后的预测性指标。此外,脉络膜不同层次的CVI研究受限于分层的准确性及测量的可重复性,人工智能等技术可能为此提供解决方案。相信未来通过更加完善的研究及人工智能的助力,CVI的内涵可进一步丰富,对DR机制的阐述以及服务于临床具有重大意义。
Diabetic retinopathy(DR)is the main cause of blindness in diabetic patients.Early diagnosis and intervention are essential to improve the quality of life of patients with DR.Choroidal vascularity index(CVI)is the ratio of choroidal luminal area to total area,which can reflect the structure and blood flow of the choroid,and has been used to evaluate the choroidal condition in various eye diseases.CVI has shown great potential in the prediction,early intervention,disease assessment,and prognosis of DR.The relationship between CVI and photoreceptors needs more research,and CVI may be used as a predictive indicator of photoreceptor health and visual prognosis.In addition,the study of CVI at different layers of the choroid is limited by the accuracy of stratification and the repeatability of measurement.Artificial intelligence and other technologies may provide solutions for this.In the future,through more comprehensive study and the help of artificial intelligence,the value of CVI will be further enriched,which is of great significance for the elucidation of the pathogenesis of DR and serving the clinic.
作者
王晓坤
吴超
崔艳艳
常威威
赵博军
Wang Xiaokun;Wu Chao;Cui Yanyan;Chang Weiwei;Zhao Bojun(Cheeloo College of Medicine,Shandong University,Jinan 250012,China;Department of Ophthalmology,Shandong Provincial Hospital,Jinan 250021,China;Department of Ophthalmology,The Second Hospital of Shandong University,Jinan 250033,China;Graduate School,Shandong First Medical University(Shandong Academy of Medical Sciences),Jinan 250117,China)
出处
《中华眼底病杂志》
CAS
CSCD
北大核心
2023年第12期1016-1021,共6页
Chinese Journal of Ocular Fundus Diseases
基金
山东省自然科学基金(ZR2019MH111)。
