摘要
我国结直肠癌患病人群众多,其中低位直肠癌占比较高。当前新辅助放化疗联合全直肠系膜切除(total mesorectal excision, TME)是国内外指南推荐的局部进展期直肠癌的标准治疗方法。在术前磁共振成像(MRI)影像学检查基础上,随着新辅助治疗具体方案的优化调整、等待-观察治疗策略的兴起以及TME相关新术式的推广应用,低位直肠癌诊疗模式不断向个体化、精准化方向推进,总体治疗目标既希望肿瘤病人获得长期生存,还要求保证足够的生活质量。此文拟对当前低位直肠癌的最新诊疗动态进行详细阐述。
Colorectal cancer is the most common cancers in China.And low rectal cancer accounts for a greater proportion.Currently a combination of neoadjuvant chemoradiotherapy and total mesorectal excision(TME)is recommended by domestic and foreign guidelines a standard treatment for locally advanced rectal cancer.Based upon preoperative examination of magnetic resonance imaging(MRI),optimization of neoadjuvant treatments,a greater popularization of"Watch&Wait"treatment strategy and new TME-related surgical procedures,a proper management of low rectal cancer continues to advance in the directions of individualization and precision.The therapeutic goals for patients with colorectal cancer are achieving long-term survival and ensuring decent quality-of-life.This review summarized the latest clinical advances of low rectal cancer.
作者
石晋瑶
杨正阳
姚宏伟
Shi Jinyao;Yang Zhengyang;Yao Hongwei(Department of General Surgery,Beijing Friendship Hospital,Capital Medical University&National Clinical Research Center for Digestive Diseases,Beijing 100050,China)
出处
《腹部外科》
2023年第6期423-429,共7页
Journal of Abdominal Surgery