摘要
目的观察血虚型腺样体伴扁桃体肥大患儿切除术术后应用芍药四物解肌汤的临床效果。方法选择2020年7月1日—2022年6月30日首都医科大学附属北京中医医院耳鼻咽喉科病房接受扁桃体伴腺样体切除术的、辨证属血虚证的患儿120例,采用随机数表法按照1∶1比例分为2组,观察组60例,术后给予口服芍药四物解肌汤口服,连续服药1周;对照组60例,术后给予头孢呋辛钠静脉滴注,每8 h 1次,连续用药1周。观察2组术后发热情况及手术前后实验室指标变化、面部表情疼痛量表(FPS-R)评分、术区伪膜情况及中医证候评分。结果观察组中度以上发热率低于对照组(P<0.05),发热时间短于对照组(P<0.05)。术后第1、第3天,2组白细胞(WBC)、C反应蛋白(CRP)水平与术前比较,差异均有统计学意义(P<0.05),2组间差异亦有统计学意义(P<0.05)。2组术前及术后4 h的FPS-R评分差异无统计学意义(P>0.05);术后第3日,观察组FPS-R评分低于对照组(P<0.05)。观察组伪膜脱落时间较对照组早(P<0.05)。术后,2组各项中医证候评分均较术前降低(P<0.05);2组面色眼睑及唇甲色白评分比较,差异无统计学意义(P>0.05);观察组头晕、乏力、大便不通评分均低于对照组,差异有统计学意义(P<0.05)。结论应用芍药四物解肌汤可减轻或避免发生扁桃体伴腺样体切除术术后不良反应,利于促进血虚型患儿术后康复。
Objective To explore the application of Shaoyao Siwu Jieji Decoction after tonsillectomy with adenoidectomy in children with tonsil and adenoid hypertrophy of blood deficiency.Methods A total of 120 children with blood deficiency syndrome who underwent tonsillectomy with adenoidectomy were randomly divided into Chinese medicine treatment group and western medicine control group according to 1∶1 ratio.The Chinese medicine treatment group was given orally Shaoyao Siwu Jieji Decoction after operation,and the western medicine control group was given intravenous injection of cefuroxime sodium after operation once every 8 hours for one week.The postoperative fever,changes of laboratory indexes before and after operation,facial expression pain scale(FPS-R)score,pseudomembrane in operation area and TCM syndrome score were observed and compared between the two groups.Results The moderate fever rate of the treatment group was lower than that of the control group(P<0.05),The duration of fever days was shorter than that of the control group(P<0.05).After treatment,the white blood cell count(WBC)and C-reactive protein concentration in the treatment group were lower than those in the control group on the first day and third day after operation and the differences were statistically significant(P<0.05),and the differences between the two groups were also statistically significant(P<0.05).After operation,the FPS-R scores of both groups were higher than those before operation(P<0.05),and the observation group was lower than the control group(P<0.05).The time of pseudomembrane shedding in the control group was later than that in the treatment group.After operation,the scores of TCM syndromes in the two groups were lower than those before operation(P<0.05).There was no significant difference between the two groups(P>0.05).The scores of dizziness,fatigue and stool obstruction syndrome in the treatment group were lower than those in the control group,and the difference was statistically significant(P<0.05).There was a statistically
作者
王雅琴
赵竞一
艾建伟
郭苏影
王俊阁
WANG Ya-qin;ZHAO Jing-yi;AI Jian-wei;GUO Su-ying;WANG Jun-ge
出处
《北京中医药》
2023年第10期1135-1138,共4页
Beijing Journal of Traditional Chinese Medicine
关键词
芍药四物解肌汤
小儿扁桃体伴腺样体肥大
扁桃体伴腺样体切除术
血虚证
Shaoyao Siwu Jieji Decoction
tonsils accompanied with adenoid hypertrophy in children
tonsillectomy with adenoidectomy
blood deficiency syndrome