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麻杏石甘汤联合多西环素治疗肺病高热患者的疗效观察

Observation on the Curative Effect of Maxingshigan Decoction Combined with Doxycycline in the Treatment of Patients with High Fever Due to Lung Disease
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摘要 目的观察麻杏石甘汤联合多西环素治疗肺病高热患者的临床疗效。方法选取2021年1月—2021年6月江门五邑中医院恩平分院收治的100例肺病高热患者作为研究对象,按照随机数表法分为对照组和观察组,每组50例。对照组给予多西环素治疗,观察组给予多西环素联合麻杏石甘汤加减治疗。比较两组的治疗效果及相关炎症指标水平变化。结果观察组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05)。观察组发热、咳嗽、咳痰临床症状消失时间均短于对照组,差异有统计学意义(P<0.05)。观察组治疗后炎症指标明显低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论麻杏石甘汤联合多西环素治疗肺病高热患者较单一使用多西环素具有明显优势,能明显缩短临床症状消失时间并降低相关炎症指标,且安全性高。 Objective To observe the clinical effect of Maxingshigan Decoction combined with doxycycline in the treatment of pulmonary fever.Methods A total of 100 patients with lung disease admitted to Enping Branch of Jiangmen Wuyi Hospital of Traditional Chinese Medicine from January 2021 to June 2021 were selected as research objects,and randomly divided into control group(n=50)and observation group(n=50).The control group was given doxycycline treatment,and the observation group was given doxycycline combined with Maxingshigan decoction plus or minus treatment.The therapeutic effect and the changes of related inflammatory indexes were compared between the two groups.Results The total response rate of the observation group was significantly higher than the control group,statistically significant(P<0.05).In the observation group,fever,cough and expectoration were significantly shorter than those in the control group,and the difference was significant(P<0.05).The inflammatory index was significantly lower than the control group,significant(P<0.05).The incidence of adverse reactions between the two groups was not significant(P>0.05).Conclusion Compared with doxycycline alone,Maxingshigan Decoction combined with dotetracycline has obvious advantages in the treatment of patients with lung disease and high fever.It can significantly shorten the time of disappearance of clinical symptoms and reduce related inflammatory indicators,with high safety.
作者 冼雪梅 邵景天 XIAN Xue-Mei;SHAO Jing-Tian(Enping Branch of JiangmenWuyi Traditional Chinese Medicine Hospital,Jiangmen Guangdong 529400,China)
出处 《中华养生保健》 2024年第1期20-23,共4页 CHINESE HEALTH CARE
基金 2021年度广东省中医药局科研项目(20201431)。
关键词 麻杏石甘汤 多西环素 肺病 高热 炎症指标 Maxing Shigan Decoction doxycycline lung disease high fever inflammatory indexs
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