摘要
目的 探讨血栓弹力图(TEG)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)和血浆纤维蛋白原(Fib)联合检测在动脉粥样硬化检测中的临床意义。方法 选取2021年6月—2022年6月在肇庆市第一人民医院心血管内科就医的动脉粥样硬化50例患者作为研究组,对照组收集健康体检者45例,无冠心病和心肌梗死等相关临床症状。运用血栓弹力图检测仪检测α角、MA值、K值和R值,应用STAR全自动凝血分析仪检测PT、APTT、TT和Fib等指标。结果 研究组的α角、MA值和FIB水平明显高于对照组,差异均具有统计学意义(P<0.01),而K值、R值、PT、APTT、TT则明显低于对照组,差异具有统计学意义(P<0.05)。结论 血栓弹力图(TEG)检测对动脉粥样硬化是一种实用而且有价值的筛查办法,可以为临床检验和诊断动脉硬化提供有效的依据。
Objective To explore clinical significance of combined detection of thromboelastography(TEG),PT,APTT and Fib for atherosclerosis patients in Zhaoqing area,and diagnostic value and clinical guiding significance of TEG of atherosclerosis.Methods The paper chose 50 atherosclerotic patients hospitalized in cardiovascular department of Zhaoqing City the First People's Hospital from June 2021 to June 2022 as study group,and 45 healthy people as control group,with no clinical symptoms of coronary heart disease and myocardial infarction.αangle,MA value,K value,and R value was detected with thromboelastography,indicators of PT,APTT,TT,and FIB were detected with STAR fully automatic coagulation analyzer.Resultsαangle,MA value and FIB level in study group was significantly higher than control group,with statistical significance(P<0.01).However,the K value,R value,PT,APTT,TT was significantly lower than control group,with statistically significant difference(P<0.05).Conclusion Thromboelastography(TEG)is a practical and valuable screening method for atherosclerosis,which can provide effective basis for clinical examination and diagnosis of atherosclerosis.
作者
王洋洋
蔡肇丽
梁丽欣
莫水群
陈立强
WANG Yangyang;CAI Zhaoi;LIANG Lixin;MO Shuiqun;CHEN Liqiang(Blood Transfusion Department,Zhaoqing City the First People's Hospital,Zhaoqing,Guangdong 526060;Zhaoqing Medical College,Zhaoqing,Guangdong 526020)
出处
《智慧健康》
2023年第24期202-204,209,共4页
Smart Healthcare
基金
肇庆市科技创新计划项目资助《肇庆地区动脉粥样硬化患者TEG、PT、APTT和Fib联合检测及其临床意义》(项目编号:2021040314006)。
