摘要
目的:基于古今医案云平台(V2.3.5)探究中医治疗中风后抑郁的用药规律。方法:计算机检索中国知网、万方数据中近20年治疗中风后抑郁的文献,建立方剂数据库,并录入到古今医案云平台(V2.3.5)中,应用软件的中药频次统计、中药属性统计、关联规则、聚类分析对数据库进行数据挖掘,并分析其规律。结果:共纳入方剂103首,涉及中药140味,中药使用的总频次是1260次,单味药使用频次高于20的药物有19味,出现频次最高的为柴胡,其次依次为郁金、甘草、川芎、石菖蒲等。用药以温、寒两性为主,味多苦、辛、甘,归经主归肝、心、脾经,其次为肺经。药物组合频次最高的为郁金-柴胡,其后依次为甘草-柴胡,白芍-柴胡,石菖蒲-郁金、川芎-柴胡等。结论:中风后抑郁的临床证型虚实夹杂,实证以中风后遗留的风、火、痰、瘀及所导致的气郁为主,虚证往往归于脏腑的虚衰,尤其是心、脾两脏。中风后抑郁临床治法应以疏肝理气解郁为基本大法,兼以活血、燥湿、化痰等法,在改善患者抑郁情绪的同时,也有助于身体恢复。
Objective:To explore the medication regularity of TCM for post-stroke depression based on Ancient and Modern medical Case Cloud Platform(V2.3.5).Methods:The literatures on the treatment of post-stroke depression in CNKI and Wanfang Database in the past 20 years were searched,and the prescription database was established and recorded in Ancient and Modern medical Case Cloud Platform(V2.3.5).The rules of literature data are analyzed,including frequency of TCM,attributes of TCM,association rules,cluster analysis.Results:A total of 103 prescriptions were included,involving 140 kinds of TCM medicine.the total frequency of use of TCM medicinal materials were 1260,there are 19 kinds of TCM medicine in which the frequency of single drug is more than 20.The occurrence frequency from high to low was Chaihu(Radix Bupleuri),Yujin(Radix Curcumae),Gancao(Radix Glycyrrhizae),Chuanxiong(Rhizoma Chuanxiong),Shichangpu(Rhizoma Acori Tatarinowii)and so on.The TCM medicine are mainly warm and cold,with bitter,acrid and sweet taste,including liver meridian,heart meridian,spleen meridian and lung meridian.The highest frequency of TCM medicine combination was Yujin-Chaihu,followed by Gancao-Chaihu,Baishao(Radix Paeoniae Alba)-Chaihu,Shichangpu-Yujin,Chuanxiong-Chaihu and so on.Conclusion:The clinical syndrome types of post-stroke depression are deficiency-excess complication.The syndrome is mainly caused by wind,fire,phlegm,blood stasis and Qi(气)depression after stroke.The syndrome of deficiency is often attributed to the deficiency of viscera,especially the heart and spleen.The clinical treatment of post-stroke depression should take soothing the liver,regulating Qi and resolving depression as the basic principle,as well as promoting blood circulation,drying dampness,resolving phlegm and other methods,which can improve the depression of patients and also help the recovery.
出处
《中医临床研究》
2023年第31期87-91,共5页
Clinical Journal Of Chinese Medicine
关键词
中风后抑郁
数据挖掘
用药规律
Post-stroke depression
Data mining
Medication regularity
