摘要
目的:探讨基于定量CT(QCT)测量腰椎骨中老年人群骨量与肝脏和椎旁肌脂肪含量的关系。方法:选取119名行肺部CT平扫联合QCT测量腰椎骨的中老年人群为研究对象,根据腰椎骨量分为骨密度(BMD)正常组(n=25)、低骨量组(n=58)和骨质疏松组(n=36)。比较各组对象肝脏和椎旁肌(竖脊肌、腰大肌和多裂肌)中脂肪含量,分析BMD与腰椎骨量、肝脏脂肪含量及椎旁肌脂肪含量的关系。结果:各组对象年龄、性别、合并症及身体质量指数(BMI)差异无统计学意义(P>0.05)。各组对象肝脏及椎旁肌脂肪含量比较,骨质疏松组>低骨量组>BMD正常组(P<0.05)。回归分析显示,肝脏脂肪含量是中老年人群骨质疏松的独立危险因素(P<0.05)。相关性分析显示,中老年人群BMD与肝脏、腰大肌、竖脊肌及多裂肌脂肪含量负相关(P<0.05),腰大肌脂肪含量与肝脏和竖脊肌脂肪含量正相关(P<0.05)。结论:中老年人群骨量与肝脏和椎旁肌脂肪含量存在一定的相关性,骨量较低的中老年人群更容易出现肝脏脂肪堆积,同时椎旁肌脂肪含量也较多。
Objective:To investigate the relationship between bone mass and liver fat content and paravertebral muscle fat content of middle-aged and elderly patients with lumbar vertebra bone by quantitative CT(QCT)measurement.Methods:119 middle-aged and elderly individuals who underwent lung CT plain scan combined with QCT measurement of lumbar spine bone were selected as the research subjects.They were divided into bone mineral density(BMD)group(n=25),low bone mass group(n=58),and osteoporosis group(n=36)according to lumbar bone mass.Fat content in liver and paravertebral muscles(erectus spinalis,psoas major and multifidus muscle)of all groups were compared,and the relationship between BMD,lumbar bone mass,liver fat content,and paravertebral muscle fat content were analyzed.Results:There were no statistically significant differences in age,sex,comorbidities or body mass index(BMI)among the groups(P>0.05).The fat content of liver and paravertebral muscle in osteoporosis group was higher than that in low bone mass group and BMD normal group,and the fat content of liver and paravertebral muscle in low bone mass group was higher than that in BMD normal group(P<0.05).Logistic analysis showed that liver fat content was an independent risk factor for osteoporosis in middle-aged and elderly people(P<0.05).Pearson correlation analysis showed that there were negative correlations between BMD and fat content in liver,psoas major,erectus spinalis and multifidus muscle(P<0.05),while there was positive correlation between fat content in psoas major and liver and erectus spinalis muscle(P<0.05).Conclusion:There is a certain correlation between bone mass and liver fat content and paravertebral muscle fat content in the middle aged and elderly population.At the same time,middle aged and elderly people with lower bone mass were more likely to have liver fat accumulation and higher paravertebral muscle fat content.
作者
包陈坚
侯珺
汪爱平
BAO Chen-jian;HOU Jun;WANG Ai-ping(Department of Radiology,Ningde Municipal Hospital of Ningde Normal University,Ningde 352100,Fujian,China;Department of Orthopedics I,Ningde Municipal Hospital of Ningde Normal University,Ningde 352100,Fujian,China)
出处
《川北医学院学报》
CAS
2023年第12期1707-1709,1713,共4页
Journal of North Sichuan Medical College
关键词
定量CT测量
中老年人
骨量
肝脏脂肪含量
椎旁肌脂肪含量
Quantitative CT measurement
Elderly
Bone mass
Liver fat content
Paravertebral muscle fat content
