摘要
在抑郁症的发生发展过程中,神经系统涉及多种复杂调节机制。针刺治疗抑郁症疗效显著,其作用机制与单胺类神经递质及其受体、下丘脑-垂体-肾上腺轴、炎症通路、氧化应激、神经可塑性、褪黑素含量密切相关。本文总结近年来针刺抗抑郁的机制研究进展,为抑郁症的治疗提供新思路。
During the occurrence and development of depression,the nervous system involves a variety of complex regulatory mechanisms.Acupuncture is effective in the treatment of depression,and its mechanism of action is closely related to monoamine neurotransmitter and their receptors,hypothalamic-pituitary-adrenal(HPA)axis,inflammatory pathway,oxidative stress,neural plasticity,and melatonin content.In this paper,we summarize the research progress of acupuncture anti-depression mechanism in recent years,and provide a new idea for the treatment of depression.
作者
梅继林
宁百乐
李晓宁
杨志新
MEI Jilin;NING Baile;LI Xiaoning;YANG Zhixin(Heilongjiang University of Chinese Medicine,Harbin 150040,China;Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510120,China;The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150001,China;Chengde Medical University,Chengde 067000,China)
出处
《中医药学报》
CAS
2023年第12期58-63,共6页
Acta Chinese Medicine and Pharmacology
基金
国家自然科学基金项目(82074522)
黑龙江省头雁团队项目基金(2019-9)
黑龙江中医药大学校级科技创新研究平台项目(2018pt03)。
关键词
抑郁症
针刺
机制
综述
Depression
Acupuncture
Mechanism
Review
