摘要
目的分析我国≥50岁经商业异性性行为感染的HIV/AIDS患者的特征,为艾滋病防控政策制定提供依据。方法数据来源于中国疾病预防控制信息系统,选取2015-2022年报告年龄≥50岁、高危行为接触史为商业异性性行为的病例,应用SPSS 24.0软件进行描述性分析,采用SaTScan10.1.2软件选用Poisson分布模型进行时空聚集性分析。结果我国报告经商业异性性行为感染HIV/AIDS患者中≥50岁所占比例从2015年45.4%上升至2022年67.8%(Cochran-Armitage趋势检验,Z=-73.96,P<0.001)。2015-2022年共报告≥50岁HIV/AIDS患者166509例,其中男性157214例(94.4%)、农民118823例(71.4%)、已婚92756例(55.7%)、小学及以下文化程度109306例(65.6%),主要分布在西南地区84940例(51.0%)和中南地区55160例(33.1%);119417例(71.7%)发现方式为医疗机构检测,107341例(64.5%)首次CD4细胞计数<350个/μL。地市级水平时空扫描分析发现,第一聚集区分布地域广泛,中心点坐标位于贵州六盘水市(26.13N,105.39E),半径达641.91 km,主要分布在西南和中南地区,聚集时段2019年(RR=5.59,P<0.001)。结论2015-2022年我国报告≥50岁商业异性性行为感染HIV/AIDS患者占比逐年增加,主要分布在西南、中南地区。建议重点地区可在原有扩大检测基础上,进一步加大主动检测力度,并针对当地特点开展综合干预措施,阻断≥50岁人群商业异性性行为传播。
Objectives To analyze the epidemiological characteristics of people living with HIV/AIDS(PLWH)aged≥50 years old who were infected by commercial heterosexual sex in China,and to provide scientific evidence for developing AIDS prevention and control policies.Methods The PLWH who reported age≥50 years old and a high-risk behavior history of commercial heterosexual sex between 2015 and 2022 were selected from the China Information System for Disease Control and Prevention.The descriptive epidemiological method was used with SPSS 24.0 software.Spatial-temporal scan statistics were calculated by SaTScan 10.1.2 using the Poisson distribution model.Results The proportion of PLWH aged≥50 years old infected by commercial heterosexual sex in China increased from 45.4%in 2015 to 67.8%in 2022(Cochran-Armitage trend test,Z=-73.96,P<0.001).From 2015 to 2022,a total of 166509 PLWH aged≥50 years old were reported,including 157214(94.4%)men,118823(71.4%)farmers,92756(55.7%)married,109306(65.6%)with primary school education or below.Among them,84940 cases(51.0%)were mainly distributed in the southwest and 55160 cases(33.1%)were in the central south of China.There were 119417 cases(71.7%)detected by medical institutions,and the first CD4+T cell counts<350 cells/μL were found in 107341 cases(64.5%).Spatial-temporal scan statistics at the prefecture and city level revealed that the first clustering areas were geographically widespread and mainly in the southwest region,with a centroid coordinate location of(26.13N,105.39E)(Liupanshui City,Guizhou)and a radius of 641.91 km,and a clustering time period of 2019(RR=5.59,P<0.001).Conclusions The proportion of reported PLWH aged≥50 years old infected by commercial heterosexual sex increased year by year from 2015 to 2022,mainly distributed in southwest and central south regions.It is suggested that on the basis of the primary expanded detection,key regions may require more efforts to improve the active and timely detection.Greater emphasis should be placed on implementing compreh
作者
秦倩倩
蔡畅
金怡晨
陈方方
李东民
汤后林
QIN Qianqian;CAI Chang;JIN Yichen;CHEN Fangfang;LI Dongmin;TANG Houlin(Division of Epidemiology,National Center for AIDS/STD Control and Prevention,China Center for Disease Control and Prevention,Beijing 102206,China)
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2023年第11期1197-1201,共5页
Chinese Journal of Aids & STD
基金
国家科技重大专项(2017ZX10201101-002-005)。
关键词
艾滋病病毒
艾滋病
流行特征
商业异性性行为
50岁及以上
HIV
AIDS
epidemiological characteristics
commercial heterosexual sex
50 years old and above
