摘要
宠物临床对犬血液肿瘤疾病的诊断主要基于病理组织学技术,目前在及时确诊方面仍有待完善。为探索系统、可靠和快速的犬血液肿瘤诊断方法,本试验拟对临床21例犬血液肿瘤疑似病例,通过血常规检查、血涂片分类计数、影像学检查、骨髓穿刺和骨髓液涂片技术综合应用以确诊肿瘤性质。结果显示,21例疑似病例被诊断为18例造血系统肿瘤和3例非造血系统肿瘤。18例造血系统肿瘤分别为5例急性淋巴细胞白血病(ALL),2例慢性淋巴细胞白血病(CLL),6例淋巴瘤,2例骨髓异常增生综合征(MDS)和3例急性粒细胞白血病(AML);3例非造血系统肿瘤均为肥大细胞瘤的骨髓转移,即肥大细胞白血病(MCL)。结果表明,临床采用血常规检查和血涂片分类计数可鉴定血液肿瘤患犬的细胞形态学异常,继之适应性应用骨髓细胞学技术辅助检查可确诊肿瘤的性质。因此,骨髓细胞学对犬血液肿瘤疾病的临床诊断具有重要辅助价值。
The diagnosis of canine hematologic tumors in pet clinical practice is mainly based on histopathological techniques,and the timely diagnosis still needs to be improved.In order to explore a systematic,reliable,and rapid diagnostic method for canine hematologic tumors,this study aimed to diagnose 21 suspected cases of canine hematologic tumors through a comprehensive application of routine blood examination,blood smear classification and counting,imaging examination,bone marrow aspiration,and bone marrow smear techniques.The results showed that among the 21 suspected cases,18 were diagnosed with hematopoietic system tumors and 3 with non-hematopoietic system tumors.The 18 hematopoietic system tumors included 5 cases of acute lymphocytic leukemia(ALL),2 cases of chronic lymphocytic leukemia(CLL),6 cases of lymphoma,2 cases of myelodysplastic syndrome(MDS),and 3 cases of acute myeloid leukemia(AML);the 3 non-hematopoietic system tumors were all bone marrow metastases of mast cell tumors,namely mast cell leukemia(MCL).The results indicate that the clinical use of routine blood examination and blood smear classification and counting can identify cytological abnormalities in dogs with hematologic tumors.Subsequently,the adaptive application of bone marrow cytology techniques as an auxiliary examination can accurately diagnose the nature of the tumor.Therefore,bone marrow cytology holds significant auxiliary value in the clinical diagnosis of canine hematologic tumors in dogs.
作者
冯如意
张艳桃
张怡雯
李冬
张璇
陈凯旋
姚华
FENG Ru-yi;ZHANG Yan-tao;ZHANG Yi-wen;LI Dong;ZHANG Xuan;CHEN Kai-xuan;YAO Hua(College of Animal Science and Technology,Beijing University of Agriculture,Beijing 102206,China;Beijing Yuetan Pet Hospital,Beijing 100045,China)
出处
《中国兽医杂志》
CAS
北大核心
2023年第11期117-122,共6页
Chinese Journal of Veterinary Medicine
关键词
犬
血液肿瘤
血常规
骨髓穿刺
细胞学
canine
hematologic tumors
blood routine examination
bone marrow aspiration
cytology
