摘要
患者在使用两性霉素B胆固醇硫酸酯复合物治疗毛霉菌感染过程中出现发热,临床药师进行不良反应关联性评价后考虑为使用两性霉素B胆固醇硫酸酯复合物引起的药物热,建议停用可疑药品。医师采纳临床药师意见,患者停用相关药物后体温降至正常。临床药师协助医师及时识别和处理药物热,避免严重药源性损害的发生,为两性霉素B胆固醇硫酸酯复合物的临床合理应用及不良反应预警提供参考。
A patient developed fever during the treatment of mucormycosis infection with amphotericin B cholesteryl sulfate complex.The clinical pharmacist considered the drug fever caused by the use of amphotericin B cholesteryl sulfate complex after evaluating the correlation of adverse reactions and suggested that the suspected drug should be stopped.The doctor accepted the advice,and the patient's temperature dropped to normal after stopping the related drugs.Clinical pharmacists assisted clinicians in identifying and dealing with drug fever in time to avoid serious drug-induced damage,and provided a reference for clinical rational application of amphotericin B cholesteryl sulfate complex and early warning of adverse reactions.
作者
胡丁元
应颖秋
程秦
杜毅鹏
沈宁
HU Ding-yuan;YING Ying-qiu;CHENG Qin;DU Yi-peng;SHENG Ning(Department of Pharmacy,Peking University Third Hospital,Beijing 100191,China;Department of Pharmacy Administration and Clinical Pharmacy,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China;Department of Respiratory and Critical Care Medicine,Peking University Third Hospital,Beijing 100191,China)
出处
《临床药物治疗杂志》
2023年第11期29-32,共4页
Clinical Medication Journal
基金
国家重点研发计划项目(2022YFC2303200)。
