摘要
目的:分析不同剂量舒芬太尼复合罗哌卡因椎管麻醉对腹腔镜结直肠癌根治患者麻醉效果及睡眠状况的影响。方法:选取2019年5月至2022年6月福建省晋江市中医院麻醉科收治的结直肠癌患者101例作为研究对象,均行腹腔镜根治术治疗,根据药物剂量的不同分成观察组(n=50)和对照组(n=51),观察组给予0.50μg/mL舒芬太尼联合0.125%罗哌卡因治疗,对照组给予0.75μg/mL舒芬太尼联合0.125%罗哌卡因治疗。应用视觉模拟评分法(VAS)对比2组患者疼痛程度,采用匹兹堡睡眠质量指数(PSQI)比较2组患者干预前后睡眠质量的变化,同时比较2组患者的麻醉效果及不良反应。结果:干预后,观察组麻醉起效时间短于对照组,观察组感觉阻滞达最高平面时间长于对照组,观察组术后3 h的VAS评分低于对照组,对照组术后第1天的PSQI评分低于观察组,观察组术后第3天的PSQI评分低于对照组,观察组(14.00%)不良反应发生率少于对照组(31.36%),差异均有统计学意义(均P<0.05)。结论:与0.75μg/mL舒芬太尼比较,0.50μg/mL舒芬太尼联合0.125%罗哌卡因的镇痛起效快,可提高患者睡眠质量,减少不良反应的发生,是一种较为理想的镇痛方法。
Objective:To analyze the effects of different doses of sufentanil combined with ropivacaine on anesthesia and sleep status of patients undergoing laparoscopic radical treatment for colorectal cancer.Methods:A total of 101 patients with colorectal cancer admitted to the Anesthesiology Department of Jinjiang Hospital of Traditional Chinese Medicine in Fujian Province from May 2019 to June 2022 were selected as the study objects.All patients underwent laparoscopic radical surgery and were divided into observation group(n=50)and control group(n=51)according to different drug doses.The observation group was treated with 0.50μg/mL sufentanil combined with 0.125%ropivacaine,while the control group was treated with 0.75μg/mL sufentanil combined with 0.125%ropivacaine.Visual Analogue Scale(VAS)was applied to compare the pain degree of the two groups.Pittsburgh Sleep Quality Index(PSQI)was used to compare the changes of sleep quality before and after the intervention,and the anesthetic effects and adverse reactions were compared between the two groups.Results:After the intervention,the onset time of anesthesia in the observation group was shorter than that in the control group,the time of sensory block reaching the highest plane in the observation group was longer than that in the control group,the VAS score at 3 h after the operation of the observation group was lower than that in the control group.The PSQI score at 1 d after the operation of the control group was lower than that in the observation group,and the PSQI score at 3 d after the operation of the observation group was lower than that in the control group.The incidence of adverse reactions in the observation group(14.00%)was lower than that in the control group(31.36%),and the difference between the two groups was statistically significant(P s<0.05).Conclusion:Compared with 0.75μg/mL sufentanil,0.50μg/mL sufentanil combined with 0.125%ropivacaine is an ideal analgesic method,which can improve patients′sleep quality and reduce the occurrence of adverse react
作者
郭志杰
陈桂培
纪腾飞
钟永灿
GUO Zhijie;CHEN Guipei;JI Tengfei;ZHONG Yongcan(Jinjiang Hospital of Traditional Chinese Medicine,Jinjiang 362200,China)
出处
《世界睡眠医学杂志》
2023年第9期2014-2017,共4页
World Journal of Sleep Medicine
关键词
舒芬太尼
罗哌卡因
椎管麻醉
腹腔镜结直肠癌根治术
麻醉效果
睡眠状况
Sufentanil
Ropivacaine
Spinal canal anesthesia
Laparoscopic radical resection of colorectal cancer
Anesthetic effect
Sleep status
