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老年女性尿流率参考值:基于全国多中心研究

Reference values for urinary flow rate in elderly women:based on a national multicenter study
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摘要 目的研究全国各地老年女性人群的尿流率数据并分析尿流率参考值范围。方法本研究自2020年7月至2022年6月入组333例受试者, 研究实施过程分为两步:第一步, 受试者填写电子化问卷, 问卷包括受试者基本信息, 尿失禁简表, 膀胱过度活动症症状评分表;第二步, 工作人员介绍移动尿流率仪的使用方法, 分发仪器及材料。尿流率数据经手机自动上传到云端数据库, 2名以上的尿控亚专科的医生进行尿流率合格筛选后进行统计学分析。结果 333例受试者入组, 移动尿流率仪采集合格尿流率记录1 375条。受试者年龄为60~84岁, 平均69岁, 尿流率参考范围分别为:尿流时间为24.8~26.2 s, 平均尿流率为12.2~12.9 ml/s, 最大尿流率22.2~23.4 ml/s, 达峰时间为8.5~9.7 s;随着年龄增长, 老年女性的最大尿流率和平均尿流率呈下降趋势(Pearson相关系数:-0.1, P<0.001)。结论老年女性的排尿速率随年龄增加而降低, 80岁以上老年女性受试者的平均尿流率较其他年龄组低, 本研究为中国老年女性的尿流率检查提供正常参考范围。 Objective To collect data on urinary flow rate in the elderly female population across the country and to analyze the range of reference values.Methods This study enrolled 333 subjects from July 2020 to June 2022.The study implementation process was divided into two steps.In the first step,subjects completed an electronic questionnaire,which included basic information about the subject,a short form for urinary incontinence,and a scoring form for the symptoms of overactive bladder syndrome.In the second step,the staff introduced the use of a mobile uroflowmetric device and distributed the instrument and materials.Uroflow rate data were automatically uploaded to a cloud database via the mobile phone.Subsequently,two or more physicians specializing in urinary control performed Uroflow rate-qualifying screenings and conducted statistical analyses.Results A total of 333 subjects were enrolled in the study,and the researchers collected 1375 qualified urine flow rate records using a mobile urine flow rate instrument.The age of the subjects ranged from 60 to 84 years,with a mean age of 69 years.The reference ranges for urinary flow rate were found to be 24.8-26.2 s.with a mean urinary flow rate of 12.2-12.9 ml/s,a maximum urinary flow rate of 22.2-23.4 ml/s,and a time to peak of 8.5-9.7 s.The study observed a tendency for both maximal and mean urinary flow rates to decrease in older women as their age increased(Pearson correlation coefficient:-O.1,P<0.001).Conclusions The uroflow rate of older women decreases with aging.Specifically,the average uroflow rate of women over 80 years old is lower than that of other age groups.This study aims to establish normal uroflow parameters for uroflowmetry in healthy older women in China.
作者 刘晓东 孟令峰 王佳文 马天明 刘敬超 黄海 王庆伟 陈敏 廖利民 沈宏 卫中庆 肖远松 潘铁军 任建 张鹏 田晓军 史本康 张耀光 Liu Xiaodong;Meng Lingfeng;Wang Jiawen;Ma Tianming;Liu Jingchao;Huang Hai;Wang Qingwei;Chen Min;Liao Limin;Shen Hong;Wei Zhongqing;Xiao Yuansong;Pan Tiejun;Ren Jian;Zhang Peng;Tian Xiaojun;Shi Benkang;Zhang Yaoguang(Department of Urology,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China;Depart ment of Urology,SUN YAT-SEN Memorial Hospital,Guangzhou 510000,China;Department of Urology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China;Department of Urology,Tongji Hospital Tongji Medical College of HUST,Wuhan 430022,China;Department of Urology,China Rehabilitation Research Center,Beijing 100020.China;Department of Urology,West China Hospital,Chengdu 610044,China;Department of Urology,The Second Affiliated Hospital of Nanjing Medical University,Nanjing 210010,China;Department of Urology,General Hospital of Southern Theatre Command,Guangshou 510000,China;Department of Urology.General Hospital of Central Theatre Command,Wuhan 430000,China;Department of Urology,China-Japan Friendship Hospital,Beijing 100029,China;Department of Urology,Beijing Chaoyang Hospital,Beijing 100020,China;Department of Urology,Peking University Third Hospital,Beijing 100191,China;Department of Urology,Qilu Hospital of Shandong University,Jinan250012.China)
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2023年第12期1406-1410,共5页 Chinese Journal of Geriatrics
基金 国家重点研发计划(2018YFC2002200) 中央高水平医院临床科研业务费(BJ-2022-098)资助。
关键词 排尿 尿动力学 参考值 多中心研究 Urination Urodynamics Reference values Multicenter study
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