摘要
脑白质高信号(WMH)为脑小血管病(CSVD)影像学特征之一,步态障碍是CSVD患者常见临床特征,WMH相关步态障碍不仅影响CSVD患者生活质量,还会增加其残疾和病死的发生风险,危及患者生命安全。目前,CSVD诊断主要依靠影像学检查,其中WMH检出率较高,且被认为与脑血管病、步态功能、认知障碍、执行功能、不良情绪及其他临床症状相关。分析并明确WMH与CSVD患者步态障碍的关系可为CSVD的临床诊治提供更多思路。
White matter hyperintensity(WMH)is one of the imaging features of cerebral small vessel disease(CSVD),and gait disorder is a common clinical feature in CSVD patients.WMH related gait disorders not only affect the quality of life of CSVD patients,but also increase the risk of disability and mortality,endangering their life safety.At present,the diagnosis of CSVD mainly relies on imaging examinations,with a high detection rate of WMH,which is believed to be related to cerebrovascular disease,gait function,cognitive impairment,executive function,adverse emotions,and other clinical symptoms.Analyzing and clarifying the relationship between WMH and gait disorders in CSVD patients can provide more insights for the clinical diagnosis and treatment of CSVD.
作者
谷家宝
冯婉君
杜敢琴
GU Jiabao;FENG Wanjun;DU Ganqin(College of Clinical Medicine,Henan University of Science and Technology,Luoyang 471003,China;Department of Neurology,the First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471003,China)
出处
《医学综述》
CAS
2023年第22期4960-4964,共5页
Medical Recapitulate
基金
河南省重大科技专项(221100210500)。
关键词
脑小血管病
步态障碍
脑白质高信号
Cerebral small vessel disease
Gait disorder
White matter hyperintensity
