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功能性近红外光谱术在针刺研究中的应用

Application of Functional Near Infrared Spectroscopy in Acupuncture Research
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摘要 针刺效应的产生与大脑的功能活动密切相关。功能性近红外光谱术(fNIRS)是根据不同血氧含量产生近红外光信号差异而成像的动态可视化技术,可无创、可视化地研究脑功能活动。目前fNIRS在针刺研究中的应用多集中在针刺对脑功能障碍相关疾病的机制探讨上,如焦虑、抑郁、轻度认知障碍(MCI)、创伤后应激障碍(PTSD)等,研究方向比较局限。在针刺研究中该技术的应用还可以进一步拓宽,包括针刺对高级神经活动或内脏功能调节的研究、经络理论的研究、得气的研究、针刺手法的研究等,发挥fNIRS的技术优势,有助于揭示更多针刺理论的科学基础和针刺效应的科学原理。同时,对fNIRS在针刺研究中关注的脑区和数据分析上做更深入的探索和挖掘,有助于揭示针刺调节脑功能的机制。 The acupuncture effect is closely related to the brain functional activity.Functional near infrared spectroscopy(fNIRS)is a dynamic and visual technology,which forms images according to the difference of near-infrared light signals generated by different blood oxygen concentrations.It can be used to explore the brain function noninvasively and visually.Currently,the application of fNIRS in acupuncture research mainly focuses on the mechanism of acupuncture on diseases related to brain dysfunction,such as anxiety,depression,mild cognitive impairment(MCI),and post-traumatic stress disorder(PTSD),with limitations.The application of fNIRS in acupuncture research can be further broadened,including regulation of higher nervous activity or visceral function,meridian theories,obtaining qi,and acupuncture manipulations,giving full play of fNIRS.This is conducive to demonstrating scientific acupuncture basis and theories.Additionally,deep exploration and mining can be conducted in different brain areas and data analysis,which helps reveal the mechanism of acupuncture in regulating brain function.
作者 李玲 马婕 宋思敏 李姝 宋慧君 李岩琪 郭义 刘阳阳 LI Ling;MA Jie;SONG Siming;LI Shu;SONG Huijun;LI Yanqi;GUO Yi;LIU Yangyang(Research Center for Experimental Acupuncture Science,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;School of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;School of Acupuncture-Massage and Tuina,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)
出处 《世界中医药》 CAS 2023年第19期2846-2850,共5页 World Chinese Medicine
基金 国家自然科学基金重点项目(82030125)——基于针刺穴位微环境物理-化学耦合网络的针效初始动力学调控机制研究。
关键词 功能性近红外光谱术 针刺研究 氧合血红蛋白 去氧血红蛋白 前额叶皮质 脑功能 认知障碍 创伤后应激障碍 Functional near infrared spectroscopy(fNIRS) Acupuncture research Oxygenated hemoglobin Deoxygenated hemoglobin Prefrontal cortex Brain function Cognitive impairment Post-traumatic stress disorder
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