摘要
亚低温治疗被推荐应用于急性大面积脑梗死。对于亚低温治疗对脑梗死的相关作用机制,近年来在抗神经细胞凋亡、维持细胞线粒体功能、调节细胞自噬、调控非编码RNA的表达、抗炎症反应等方面有一定的研究进展,本文就亚低温治疗脑梗死机制的研究进展进行综述,以推动亚低温在脑梗死治疗中的应用。
Mild hypothermia therapy had been recommended for acute massive cerebral infarction.In recent years,there has been some research progress on the mechanism of mild hypothermia therapy on cerebral infarction,including anti-apoptosis,maintenance of mitochondrial function,regulation of autophagy,regulation of expression of non-coding RNA,and anti-inflammation effect.In order to promote the application of mild hypothermia therapy in the treatment of cerebral infarction,this paper reviewed the research progress on the mechanism of mild hypothermia therapy.
作者
邱甜
杨苗娟
胡波
郭毅
何奕涛
Qiu Tian;Yang Miaojuan;Hu Bo;Guo Yi;He Yitao(Department of Neurology,the Second Clinical Medical College of Jinan University,Shenzhen 518020,China;Shenzhen Clinical Research Centre for Geriatrics,Shenzhen 518020,China)
出处
《中华脑血管病杂志（电子版）》
2023年第5期518-521,共4页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
基金
国家自然科学基金面上项目(82071463)。
关键词
亚低温治疗
脑梗死
细胞凋亡
自噬
线粒体
非编码RNA
Mild hypothermia therapy
Cerebral infarction
Cell apoptosis
Autophagy
Mitochondria
Non-coding RNA
