摘要
目的:分析彩色多普勒超声下子宫动脉舒张早期切迹对不良母婴结局的预测价值。方法:选取2022年1月—12月扬州市妇幼保健院超声科收治的孕22~24周初产妇为研究对象,共90例,全部研究对象于孕22~24^(+6)周进行1次彩色多普勒超声双侧子宫动脉检测,依据治疗、随访期间是否出现不良母婴结局事件,分为母婴结局不良组(n=24)与母婴结局良好组(n=66)。所有研究对象观察随访至胎儿出生后4周。比较两组妊娠结局及婴儿体征参数,采用受试者工作特征(ROC)曲线分析妊娠中期双侧子宫动脉舒张早期切迹在不良母婴结局的曲线下面积(AUC),采用二元Logistic回归模型分析妊娠中期双侧子宫动脉舒张早期切迹在不良母婴结局的临床相关性。结果:90例初产妇共发生单纯生长受限3例、先天性心脏病1例、双肾集合系统分离1例、巨大儿4例、新生儿窒息3例、胎盘早剥4例、胎儿窘迫8例,总发生24例,母婴结局不良发生率26.67%(24/90)。两组间超声动脉切迹发生率差异有统计学意义(P <0.05)。ROC曲线分析显示双侧子宫动脉舒张早期切迹评估不良母婴结局AUC为0.850,灵敏度为96.7%,特异度为26.7%,95%置信区间为0.750~0.950,具备检测效能(P<0.001)。二元Logistic回归模型提示:妊娠中期双侧子宫动脉舒张早期切迹是不良母婴结局事件的危险因素(P <0.05)。结论:超声检出子宫动脉单侧或双侧舒张早期切迹,与不良母婴结局相关,对其有一定的预判作用。
Objective To analyze the predictive value of uterine artery early diastolic notch under color Doppler ultrasound for adverse maternal and infant outcomes.Methods A total of 90 primigravidae aged 22 to 24 weeks of pregnancy admitted to the Department of Ultrasound of Yangzhou Maternal and Child Care Service Center from January 2022 to December 2022 were selected+6 for the study.All the study subjects underwent one color Doppler ultrasound bilateral uterine artery detection in the 22 to 24 weeks of gestation and were classified into the group of poor maternal and infant outcomes(n=24)and the group of good maternal and infant outcomes(n=66)according to whether there were adverse maternal and infant outcome events during the period of treatment and follow up.All subjects were observed and followed up until 4 weeks after the birth of the fetus.The pregnancy outcomes and infant signs were compared between the two groups.The receiver operating characteristic(ROC)curves were analyzed to determine the risk of adverse maternal and infant outcomes in the mid-pregnancy bilateral uterine arteries.The area under the curve(AUC)of early diastolic notch in adverse maternal and infant outcomes was analyzed,and the clinical relevance of mid-gestation bilateral uterine artery early diastolic notch in adverse maternal and infant outcomes was analyzed by binary Logistic regression model.Results A total of 90 primigravidae had 3 cases of simple growth restriction,1 case of congenital heart disease,1 case of separation of the collecting system of both kidneys,4 cases of macrosomia,3 cases of neonatal asphyxia,4 cases of placental abruption,and 8 cases of fetal distress,for a total incidence of 24,and an incidence of adverse maternal and infant outcomes of 26.67%(24/90).The difference in the incidence of ultrasonic arterial notch between the two groups was statistically significant(P<0.05).ROC curve analysis showed that bilateral uterine arterial early diastolic notch to assess adverse maternal and infant outcomes had an AUC of 0.850,a s
作者
黄鲜梅
黄帝
陈飞
HUANG Xianmei;HUANG Di;CHEN Fei(Department of Ultrasound,Yangzhou Maternal and Child Care Service Center,Yangzhou,Jiangsu 225002,China)
出处
《影像研究与医学应用》
2023年第19期14-17,共4页
Journal of Imaging Research and Medical Applications
关键词
子宫动脉舒张早期切迹
妊娠
初产妇
不良母婴结局
临床相关性
Uterine artery early diastolic notch
Pregnancy
Primigravida
Adverse maternal and infant outcomes
Clinical correlation
