摘要
目的:探讨心理应激对2型糖尿病患者神经内分泌、血压、血糖及免疫功能的影响。方法:选取2018年2月—2019年2月北京市昌平区回龙观社区卫生服务中心收治的2型糖尿病患者72例为观察对象,依据症状自评量表将存在心理应激的患者36例设定为研究组,将无心理应激的患者36例设定为对照组。比较两组患者血清神经内分泌、血压、血糖、免疫功能指标。结果:研究组神经内分泌指标高于对照组,差异有统计学意义(P<0.05);研究组CD4+、CD8+、CD4+/CD8+水平高于对照组,差异有统计学意义(P<0.05);0.5、1、2 h时,研究组血糖和基础值的差值高于对照组,差异有统计学意义(P<0.05);0.5、1、2、3h时,研究组SBP、DBP差值高于对照组,差异有统计学意义(P<0.05)。结论:心理应激可对2型糖尿病患者神经内分泌、血糖、血压、免疫功能产生影响。
Objective:To explore the effects of psychological stress on neuroendocrine,blood pressure,blood glucose and immune function in patients with type 2 diabetes mellitus.Methods:Seventy-two cases of type 2 diabetes mellitus patients admitted to Beijing Changping District Huilongguan Community Health Center from February 2018 to February 2019 were selected as observation subjects.Based on the symptom self-assessment scale,thirty-six patients with psychological stress were set as the study group,and thirty-six patients without psychological stress were set as the control group.Comparison of serum neuroendocrine,blood pressure,blood glucose,immune function indexes in the two groups.Results:The neuroendocrine indexes of the study group were higher than those of the control group,and the difference was statistically significant(P<0.05);The levels of CD4+,CD8+,CD4+/CD8+in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05);At 0.5,1 and 2 h,the difference between blood glucose and basal values in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05);At 0.5,1,2 and 3 h,the difference between SBP and DBP in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Psychological stress can affect neuroendocrine,blood glucose,blood pressure,and immune function in type 2 diabetes mellitus patients.
作者
吴雪松
Wu Xuesong(Beijing Changping District Huilongguan Community Health Center,Beijing 100096,China)
出处
《中外医药研究》
2023年第19期57-59,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
心理应激
2型糖尿病
神经内分泌
免疫功能
Psychological stress
Type 2 diabetes mellitus
Neuroendocrine
Immune function
