摘要
目的探究难治性幽门螺杆菌(helicobacter pylori,HP)感染的影响因素分析。方法选取2018年1月—2023年5月高邮市中医医院消化内科纳入的80例难治性HP感染阳性患者为研究对象,均进行根除治疗,根据根除的效果分为根除成功组(n=56)、根除失败组(n=28),分析在不同因素的影响下HP根除率,并采用Logistic回归分析进行多因素分析。结果经分析显示,在不同居住地、不同DOB值及用药情况的HP根治疗效差具有统计学意义(P<0.05),而对于不同性别、年龄、是否吸烟、饮酒、不同疾病类型、是否在家用餐等因素的影响下根治疗效差异无统计学意义(P>0.05);经Logistic回归分析显示,居住地(OR=3.03)、治疗前DOB(OR=1.76)、规律用药(OR=4.12)为影响非抗生素治疗HP感染根除率的独立因素(P<0.05)。结论居住地、治疗前DOB、规律用药是影响非抗生素治疗难治性幽门螺杆菌感染的独立影响因素。
Objective To explore the influencing factors of refractory Helicobacter pylori(HP)infection.Methods From January 2018 to May 2023,80 patients with refractory HP infection in the Department of Gastroenterology,Gaoyou Hospital of Traditional Chinese Medicine were selected as the research objects.All patients were treated with eradication therapy.According to the effect of eradication,they were divided into successful eradication group(n=56)and failed eradication group(n=28).The eradication rate of HP under the influence of different factors was analyzed,and Logistic regression analysis was used for multivariate analysis.Results The analysis showed that the curative effect of HP in different places of residence,different DOB values and medication was statistically significant(P<0.05).Logistic regression analysis showed that residence(OR=3.03),DOB before treatment(OR=1.76)and regular medication(OR=4.12)were independent factors affecting the eradication rate of HP infection in non-antibiotic treatment(P<0.05).Conclusion Residence,DOB before treatment and regular medication were independent factors influencing non-antibiotic treatment of refractory Helicobacter pylori infection.
作者
金玉琳
JIN Yulin(Department of Gastroenterology,Gaoyou Hospital of Traditional Chinese Medicine,Gaoyou,Jiangsu Province,225600 China)
出处
《系统医学》
2023年第16期95-97,101,共4页
Systems Medicine
关键词
难治性幽门螺杆菌感染
根除效果
影响因素
规律用药
Refractory Helicobacter pylori infection
Eradication effect
Influencing factors
Regular medication
